Publications

  • Nawale, Ganesh N.; Bahadorikhalili, Saeed; Sengupta, Pallabi; Kadekar, Sandeep et al.

    4 '-Guanidinium-modified siRNA: a molecular tool to control RNAi activity through RISC priming and selective antisense strand loading

    Part of Chemical Communications, p. 9112-9115, 2019.

    Open access
  • Mittapelli, Lavanya L.; Nawale, Ganesh N.; Gholap, Sachin P.; Varghese, Oommen P. et al.

    A turn-on fluorescent GFP chromophore analog for highly selective and efficient detection of H2S in aqueous and in living cells

    Part of Sensors and actuators. B, Chemical, 2019.

  • Paidikondala, Maruthibabu; Rangasami, Vignesh Kumar; Nawale, Ganesh N.; Casalini, Tommaso et al.

    An Unexpected Role of Hyaluronic Acid in Trafficking siRNA Across the Cellular Barrier: The First Biomimetic, Anionic, Non-Viral Transfection Method

    Part of Angewandte Chemie International Edition, p. 2815-2819, 2019.

  • Paidikondala, Maruthibabu; Wang, Shujiang; Hilborn, Jöns; Larsson, Sune et al.

    Impact of Hydrogel Cross-Linking Chemistry on the in Vitro and in VivoBioactivity of Recombinant Human Bone Morphogenetic Protein-2

    Part of ACS Applied Bio Materials, 2019.

  • Wang, Shujiang; Nawale, Ganesh N.; Oommen, Oommen P.; Hilborn, Jöns et al.

    Influence of ions to modulate hydrazone and oxime reaction kinetics to obtain dynamically cross-linked hyaluronic acid hydrogels

    Part of Polymer Chemistry, p. 4322-4327, 2019.

    Open access
  • Paidikondala, Maruthibabu; Kadekar, Sandeep; Varghese, Oommen P.

    Innovative strategy for 3D transfection of primary human stem cells with BMP-2 expressing plasmid DNA: A clinically translatable strategy for ex vivogene therapy

    Part of International Journal of Molecular Sciences, 2019.

    Open access
  • Paidikondala, Maruthibabu; Nawale, Ganesh N.; Varghese, Oommen P.

    Insights into siRNA Transfection in Suspension: Efficient Gene Silencing in Human Mesenchymal Stem Cells Encapsulated in Hyaluronic Acid Hydrogel

    Part of Biomacromolecules, p. 1317-1324, 2019.

  • Han, Yuanyuan; Qiu, Zhen; Nawale, Ganesh N.; Varghese, Oommen P. et al.

    MicroRNA detection based on duplex-specific nuclease-assisted target recycling and gold nanoparticle/graphene oxide nanocomposite-mediated electrocatalytic amplification

    Part of Biosensors & bioelectronics, p. 188-193, 2019.

  • Bermejo-Velasco, Daniel; Azémar, Alice; Oommen, Oommen P.; Hilborn, Jöns et al.

    Modulating thiol pKa promotes disulfide formation at physiological pH: An elegant strategy to design disulfide cross-linked hyaluronic acid hydrogels

    Part of Biomacromolecules, p. 1412-1420, 2019.

  • Kadekar, Sandeep; Nawale, Ganesh N.; Karlsson, Kira; Ålander, Cecilia et al.

    Synthetic design of asymmetric miRNA with engineered 3′-overhang to improve strand selection

    Part of Molecular Therapy - Nucleic Acids, p. 597-604, 2019.

    Open access
  • Ferreira, Silvia A; Motwani, Meghna S; Faull, Peter A; Seymour, Alexis J et al.

    Bi-directional cell-pericellular matrix interactions direct stem cell fate

    Part of Nature Communications, 2018.

    Open access
  • Wang, Shujiang; Nawale, Ganesh N.; Kadekar, Sandeep; Oommen, Oommen P. et al.

    Saline Accelerates Oxime Reaction with Aldehyde and Keto Substrates at Physiological pH

    Part of Scientific Reports, 2018.

    Open access
  • Yan, Hongji; Casalini, Tommaso; Hulsart Billström, Gry; Wang, Shujiang et al.

    Synthetic design of growth factor sequestering extracellular matrix mimetic hydrogel for promoting in vivo bone formation

    Part of Biomaterials, p. 190-202, 2018.

  • Bermejo-Velasco, Daniel; Nawale, Ganesh N.; Oommen, Oommen P.; Hilborn, Jöns et al.

    Thiazolidine chemistry revisited: a fast, efficient and stable click-type reaction at physiological pH

    Part of Chemical Communications, p. 12507-12510, 2018.

    Open access
  • Todeschi, Maria R.; El Backly, Rania M.; Varghese, Oommen P.; Hilborn, Jöns et al.

    Host cell recruitment patterns by bone morphogenetic protein-2 releasing hyaluronic acid hydrogels in a mouse subcutaneous environment

    Part of Regenerative Medicine, p. 525-539, 2017.

  • Roshanbinfar, Kaveh; Hilborn, Jöns; Varghese, Oommen P.; Oommen, Oommen P.

    Injectable and thermoresponsive pericardial matrix derived conductive scaffold for cardiac tissue engineering

    Part of RSC Advances, p. 31980-31988, 2017.

    Open access
  • Gurav, Deepanjali; Varghese, Oommen P.; Hamad, Osama A.; Nilsson, Bo et al.

    Chondroitin sulfate coated gold nanoparticles: a new strategy to resolve multidrug resistance and thromboinflammation

    Part of Chemical Communications, p. 966-969, 2016.

  • Varghese, Oommen P.; Liu, Jianping; Sundaram, Karthi; Hilborn, Jöns et al.

    Chondroitin sulfate derived theranostic nanoparticles for targeted drug delivery

    Part of Biomaterials Science, p. 1310-1313, 2016.

  • Oommen, Oommen Podiyan; Duehrkop, Claudia; Nilsson, Bo; Hilborn, Jöns et al.

    Multifunctional Hyaluronic Acid and Chondroitin Sulfate Nanoparticles: Impact of Glycosaminoglycan Presentation on Receptor Mediated Cellular Uptake and Immune Activation

    Part of ACS Applied Materials and Interfaces, p. 20614-20624, 2016.

  • Barman, Jharna; Gurav, Deepanjali; Oommen, Oommen Podiyan; Varghese, Oommen P.

    2 '-N-Guanidino, 4 '-C-ethylene bridged thymidine (GENA-T) modified oligonucleotide exhibits triplex formation with excellent enzymatic stability

    Part of RSC Advances, p. 12257-12260, 2015.

  • Yan, Hongji; Podiyan, Oommen; Yu, Di; Hilborn, Jöns et al.

    Chondroitin Sulfate-Coated DNA-Nanoplexes Enhance Transfection Efficiency by Controlling Plasmid Release from Endosomes: A New Insight into Modulating Nonviral Gene Transfection

    Part of Advanced Functional Materials, p. 3907-3915, 2015.

  • Wang, Shujiang; Gurav, Deepanjali; Oommen, Oommen Podiyan; Varghese, Oommen P

    Insights into the Mechanism and Catalysis of Oxime Coupling Chemistry at Physiological pH

    Part of Chemistry - A European Journal, p. 5980-5985, 2015.

  • Yang, Hsiao-yin; Vonk, Lucienne A.; Licht, Ruud; van Boxtel, Antonetta M. G. et al.

    Cell type and transfection reagent-dependent effects on viability, cell content, cell cycle and inflammation of RNAi in human primary mesenchymal cells

    Part of European Journal of Pharmaceutical Sciences, p. 35-44, 2014.

  • Backly, R. E.; Todeschi, M. R.; Varghese, Oommen; Hilborn, Jöns et al.

    Host cell recruitment patterns by BMP-2 releasing hyaluronic acid gels in a mouse subcutaneous model

    Part of Journal of Tissue Engineering and Regenerative Medicine, p. 65-65, 2014.

  • Podiyan, Oommen; Garousi, Javad; Sloff, Marije; Varghese, Oommen

    Tailored Doxorubicin-Hyaluronan Conjugate as a Potent Anticancer Glyco-Drug: An Alternative to Prodrug Approach

    Part of Macromolecular Bioscience, p. 327-333, 2014.

  • Wang, Shujiang; Oommen, Oommen P.; Yan, Hongji; Varghese, Oommen P.

    Mild and Efficient Strategy for Site-Selective Aldehyde Modification of Glycosaminoglycans: Tailoring Hydrogels with Tunable Release of Growth Factor

    Part of Biomacromolecules, p. 2427-2432, 2013.

  • Rahman, Cheryl V.; Kuhn, Gisela; White, Lisa J.; Kirby, Giles T. S. et al.

    PLGA/PEG-hydrogel composite scaffolds with controllable mechanical properties

    Part of Journal of Biomedical Materials Research. Part B - Applied biomaterials, p. 648-655, 2013.

  • Oommen, Oommen P.; Wang, Shujiang; Kisiel, Marta; Sloff, Marije et al.

    Smart Design of Stable Extracellular Matrix Mimetic Hydrogel: Synthesis, Characterization, and In Vitro and In Vivo Evaluation for Tissue Engineering

    Part of Advanced Functional Materials, p. 1273-1280, 2013.

  • Kisiel, Marta; Ventura, M.; George, Anu; Hilborn, Jöns et al.

    Critical Assessment of rhBMP-2 Mediated Bone Induction: an In Vitro and In Vivo Evaluation

    Part of Journal of Tissue Engineering and Regenerative Medicine, p. 39-39, 2012.

  • Kisiel, Marta; Ventura, Manuela; Podiyan, Oommen; George, Anu et al.

    Critical assessment of rhBMP-2 mediated bone induction: An in vitro and in vivo evaluation.

    Part of Journal of Controlled Release, p. 646-653, 2012.

  • Varghese, Oommen P.; Podiyan, Oommen; Wang, S; Kisiel, Marta et al.

    Injectable hyaluronic acid hydrogel for bone tissue engineering

    Part of European Cells and Materials, p. 2-, 2012.

  • Hilborn, Jöns; Varghese, Oommen P.; Jeronimo, B.

    Keynote: Safe and efficient in-vivo gene gene transfer and silencing technologies using natural pathways

    Part of Journal of Tissue Engineering and Regenerative Medicine, p. 190-190, 2012.

  • Martinez-Sanz, Elena; Varghese, Oommen; Kisiel, Marta; Engstrand, Thomas et al.

    Minimally invasive mandibular bone augmentation using injectable hydrogels

    Part of Journal of Tissue Engineering and Regenerative Medicine, p. s15-s23, 2012.

  • Podiyan, Oommen; Wang, Shujiang; Kisiel, Marta; Hilborn, Jöns et al.

    Smart design of stable hydrazone crosslinked extracellular matrix mimetic hydrogel for tissue engineering application

    Part of Journal of Tissue Engineering and Regenerative Medicine, p. 192-192, 2012.

  • Martinez-Sanz, Elena; Ossipov, Dmitri A.; Hilborn, Jöns; Larsson, Sune et al.

    Bone reservoir: Injectable hyaluronic acid hydrogel for minimal invasive bone augmentation

    Part of Journal of Controlled Release, p. 232-240, 2011.

  • Ossipov, Dmitri A.; Piskounova, Sonya; Varghese, Oommen P.; Hilborn, Jöns

    Functionalization of Hyaluronic Acid with Chemoselective Groups via a Disulfide-Based Protection Strategy for In Situ Formation of Mechanically Stable Hydrogels

    Part of Biomacromolecules, p. 2247-2254, 2010.

  • Ossipov, Dmitri A.; Yang, Xia; Varghese, Oommen; Kootala, Sujit et al.

    Modular approach to functional hyaluronic acid hydrogels using orthogonal chemical reactions

    Part of Chemical Communications, p. 8368-8370, 2010.

  • Varghese, Oommen P.; Kisiel, Marta; Martinez-Sanz, Elena; Ossipov, Dmitri A. et al.

    Synthesis of Guanidinium-Modified Hyaluronic Acid Hydrogel

    Part of Macromolecular rapid communications, p. 1175-1180, 2010.

  • Varghese, Oommen P.; Sun, Weilun; Hilborn, Jöns; Ossipov, Dmitri A.

    In Situ Cross-Linkable High Molecular Weight Hyaluronan−Bisphosphonate Conjugate for Localized Delivery and Cell-Specific Targeting: A Hydrogel Linked Prodrug Approach

    Part of Journal of the American Chemical Society, p. 8781-8783, 2009.

  • Honcharenko, Dmytro; Barman, Jharna; Varghese, Oommen P.; Chattopadhyaya, Jyoti

    Comparison of the RNase H Cleavage Kinetics and Blood Serum Stability of the North-Conformationally Constrained and 2‘-Alkoxy Modified Oligonucleotides

    Part of Biochemistry, p. 5635-5646, 2007.

  • Varghese, Oommen P.; Barman, Jharna; Pathmasiri, Wimal; Plashkevych, Oleksandr et al.

    Conformationally Constrained 2'-N,4'-C-Ethylene-Bridged Thymidine (Aza-ENA-T): Synthesis, Structure, Physical, and Biochemical Studies of Aza-ENA-T-Modified Oligonucleotides

    Part of Journal of the American Chemical Society, p. 15173-15187, 2006.

  • Honcharenko, D.; Varghese, O.P.; Plashkevych, O.; Barman, J. et al.

    Synthesis and Structure of Novel Conformationally-constrained 1'2'-Azetidine-Fused Bicyclic Pyrimidine Nucleosides: Their Incorporation into Oligo-DNAs and the Thermal Stability of the Heteroduplexes

    Part of Journal of Organic Chemistry, p. 299-314, 2006.

  • Chatterjee, S.; Pathmasiri, W.; Plashkevych, O.; Honcharenko, D. et al.

    The chemical nature of the 2'-substituent in the pentose-sugar dictates the pseudoaromatic character of the nucleobase (pKa) in DNA/RNA.

    Part of Org. Biomol. Chem., p. 1675 1675-1686 1686, 2006.

  • Chatterjee, Subhrangsu; Pathmasiri, Wimal; Plashkevych, Oleksandr; Honcharenko, D. et al.

    The chemical nature of the 2'-substituent in the pentosesugar dictates the pseudoaromatic character of the nucleobase (pKa) in DNA/RNA

    Part of Org Biomol Chem, p. 1675-1686, 2006.

  • Bermejo, Daniel; Kadekar, Sandeep; Tavares da Costa, Marcus Vinicius; Podiyan, Oommen et al.

    First Aldol-Crosslinked Hyaluronic Acid Hydrogel: Fast and Hydrolytically Stable Gel with Tissue Adhesive Properties

    Part of Chemical Sciences Journal

  • Wang, Shujiang; Nawale, Ganesh N.; Kadekar, Sandeep; Oommen, Oommen P. et al.

    Saline catalyse oxime reaction at physiological pH: overcoming a major limitation of bioorthogonal reaction

    Open access