Molecular interactions, enzymology and drug discovery

The goal of our research is to increase our knowledge about molecular interactions and their dynamics. This is fundamental to the understanding of how biological systems function and are regulated, which can be utilized in the development of new effective and safe drugs. The research focuses on different types of enzymes, the proteins that catalyze chemical reactions in nature. The enzymes we study are all relevant to diseases where there are currently no effective drugs, e.g. cancer and infectious diseases.

The research requires new methods, instruments and strategies. We have in particular been involved in the development of biosensors for the study of molecular interactions. Our studies help solve fundamental scientific questions regarding molecular recognition, with a strong focus on their dynamics and how they can be regulated. There are many  important applications, especially in the pharmaceutical industry.

Professor Helena Danielson, research leader

Ongoing research