Research Groups within Organic Chemistry
Targeting Hypoxia in Cancer Therapy and Diagnosis - Organic synthesis of luminescent heterocyclic compounds, target-specific imaging agents, and hypoxia-activated prodrugs.
Halogen Bonding, NMR Method Development, Antibiotic Resistance and Natural Product Chemistry - Halogen bonding, antimalarial natural products from plants in East Africa, paramagnetic ligand tagging technology and development of Metallo-Beta-Lactamase inhibitors to control antibiotic resistance.
Graphene from a Molecular Perspective - Purification, derivatisation and evaluations of fullerenes and carbon nanotubes; synthesis and chemical functionalization of graphene. Dyes and dyads for electron transfer studies, solar cells and molecular electronics applications. Supramolecular & organometallic chemistry.
Functional Molecular Entities - Organic synthesis of functional entities: Supramolecular host-guest systems, photoswitchable peptidomimetics, and monomers for conducting redox polymers. Our main tools are organometallic synthesis, peptide synthesis, and NMR spectroscopy.
Chemical Tools for Research and Drug Discovery Beyond Traditional Drug Space - Chemical probes for difficult targets that conquer complex disease.
Quantum Chemistry - Electronic structure and dynamics simulations, and modelling of electronic structure theory plays a central role in our research projects. Current applications include simulations of properties of chemiluminescent molecules, photochemistry, and interpretation of spectra. Developments are focused on multi-configurational wave function theory and their implementations in the software package OpenMolcas.
Synthetic Methodology, Catalysis and Green Chemistry - The group pursues the development of faster, cheaper and greener organic transformations using C-H activation, arynes and mechanochemistry.
Catalysis, Synthesis, Organometallics, Mechanisms - We are interested in developing new methods and catalysts for the realization of challenging transformations in organic chemistry. Moreover, we carry out in-depth mechanistic studies in order to understand and further advance transition-metal-catalyzed reactions.