Publications

Intramolecular alkene-alkyne metathesis and 1,4-cis-hydrogenation as a stereocontrolled route to compounds with exocyclic double bonds

Vasil'ev, A. A.; Engman, Lars; Serebryakov, E. P.

Part of Russian chemical bulletin, p. 169-171, 2020.

DOI for Intramolecular alkene-alkyne metathesis and 1,4-cis-hydrogenation as a stereocontrolled route to compounds with exocyclic double bonds

Chain-Breaking Phenolic 2,3-Dihydrobenzo[b]selenophene Antioxidants: Proximity Effects and Regeneration Studies

Singh, Vijay P.; Yan, Jiajie; Poon, Jia-fei; Gates, Paul J. et al.

Part of Chemistry - A European Journal, p. 15080-15088, 2017.

DOI for Chain-Breaking Phenolic 2,3-Dihydrobenzo[b]selenophene Antioxidants: Proximity Effects and Regeneration Studies

Substituent Effects in Chain-Breaking Aryltellurophenol Antioxidants

Poon, Jia-fei; Yan, Jiajie; Jorner, Kjell; Ottosson, Henrik et al.

Part of Chemistry - A European Journal, p. 3520-3527, 2018.

DOI for Substituent Effects in Chain-Breaking Aryltellurophenol Antioxidants

Incorporation and delivery of an organoselenium antioxidant from a brushite cement

Pujari-Palmer, Shiuli; Lu, Xi; Singh, Vijay P.; Engman, Lars et al.

Part of Materials letters (General ed.), p. 115-119, 2017.

DOI for Incorporation and delivery of an organoselenium antioxidant from a brushite cement

Selenium- and Tellurium-Based Antioxidants for Modulating Inflammation and Effects on Osteoblastic Activity

Lu, Xi; Mestres, Gemma; Singh, Vijay Pal; Effati, Pedram et al.

Part of Antioxidants, 2017.

Selenium- and tellurium-based antioxidants for modulating inflammation and effects on osteoblastic activity

Lu, Xi; Mestres, Gemma; Singh, Vijay Pal; Effati, Pedram et al.

Part of Antioxidants, p. 1-13, 2017.

DOI for Selenium- and tellurium-based antioxidants for modulating inflammation and effects on osteoblastic activity Download full text (pdf) of Selenium- and tellurium-based antioxidants for modulating inflammation and effects on osteoblastic activity

Nitro-, Azo-, and Amino Derivatives of Ebselen: Synthesis, Structure, and Cytoprotective Effects

Singh, Vijay P.; Poon, Jia-fei; Yan, Jiajie; Lu, Xi et al.

Part of Journal of Organic Chemistry, p. 313-321, 2017.

DOI for Nitro-, Azo-, and Amino Derivatives of Ebselen: Synthesis, Structure, and Cytoprotective Effects

Alkyltelluro Substitution Improves the Radical-Trapping Capacity of Aromatic Amines

Poon, Jia-Fei; Yan, Jiajie; Singh, Vijay P; Gates, Paul J et al.

Part of Chemistry - A European Journal, p. 12891-12903, 2016.

DOI for Alkyltelluro Substitution Improves the Radical-Trapping Capacity of Aromatic Amines

Regenerable Radical-Trapping Tellurobistocopherol Antioxidants

Poon, Jia-fei; Yan, Jiajie; Singh, Vijay P.; Gates, Paul J. et al.

Part of Journal of Organic Chemistry, p. 12540-12544, 2016.

DOI for Regenerable Radical-Trapping Tellurobistocopherol Antioxidants

Ebselen and analogs as inhibitors of Bacillus anthracis thioredoxin reductase and bactericidal antibacterials targeting Bacillus species, Staphylococcus aureus and Mycobacterium tuberculosis

Gustafsson, Tomas; Osman, Harer; Werngren, Jim; Hoffner, Sven et al.

Part of Biochimica et Biophysica Acta - General Subjects, p. 1265-1271, 2016.

DOI for Ebselen and analogs as inhibitors of Bacillus anthracis thioredoxin reductase and bactericidal antibacterials targeting Bacillus species, Staphylococcus aureus and Mycobacterium tuberculosis

Multifunctional Antioxidants: Regenerable Radical-Trapping and Hydroperoxide-Decomposing Ebselenols

Kumar, Shailesh; Yan, Jiajie; Poon, Jia-fei; Singh, Vijay P et al.

Part of Angewandte Chemie International Edition, p. 3729-3733, 2016.

DOI for Multifunctional Antioxidants: Regenerable Radical-Trapping and Hydroperoxide-Decomposing Ebselenols

The Cellular Thioredoxin-1/Thioredoxin Reductase-1 Driven Oxidoreduction Represents a Chemotherapeutic Target for HIV-1 Entry Inhibition

Reiser, Kathrin; Mathys, Leen; Curbo, Sophie; Pannecouque, Christophe et al.

Part of PLOS ONE, 2016.

DOI for The Cellular Thioredoxin-1/Thioredoxin Reductase-1 Driven Oxidoreduction Represents a Chemotherapeutic Target for HIV-1 Entry Inhibition Download full text (pdf) of The Cellular Thioredoxin-1/Thioredoxin Reductase-1 Driven Oxidoreduction Represents a Chemotherapeutic Target for HIV-1 Entry Inhibition

Regenerable thiophenolic radical-trapping antioxidants

Yan, Jiajie; Poon, Jia-fei; Singh, Vijay P; Gates, Paul et al.

Part of Organic Letters, p. 6162-6165, 2015.

DOI for Regenerable thiophenolic radical-trapping antioxidants

Effect of a Bromo Substituent on the Glutathione Peroxidase Activity of a Pyridoxine-like Diselenide

Singh, Vijay P; Poon, Jia-fei; Butcher, Ray J.; Lu, Xi et al.

Part of The Journal of Organic Chemistry, p. 7385-7395, 2015.

DOI for Effect of a Bromo Substituent on the Glutathione Peroxidase Activity of a Pyridoxine-like Diselenide

Organochalcogen stabilizers efficiently protect model polyolefins exposed to chlorinated media

Kirchhain, Arno; Yu, Wenbin; Engman, Lars

Part of Polymer degradation and stability, p. 82-87, 2015.

DOI for Organochalcogen stabilizers efficiently protect model polyolefins exposed to chlorinated media

Regenerable Antioxidants - Introduction of Chalcogen Substituents into Tocopherols

Poon, Jia-fei; Singh, Vijay P; Yan, Jiajie; Engman, Lars

Part of Chemistry - A European Journal, p. 2447-2457, 2015.

DOI for Regenerable Antioxidants - Introduction of Chalcogen Substituents into Tocopherols

Scavenging effect of Trolox released from brushite cements

Mestres, Gemma; Santos, Carlos F; Engman, Lars; Persson, Cecilia et al.

Part of Acta Biomaterialia, p. 459-466, 2015.

DOI for Scavenging effect of Trolox released from brushite cements

Pyridoxine-derived organoselenium compounds with glutathione peroxidase-like and chain-breaking antioxidant activity

Singh, Vijay; Poon, Jia-fei; Butcher, Ray; Engman, Lars

Part of Chemistry - A European Journal, p. 12563-12571, 2014.

DOI for Pyridoxine-derived organoselenium compounds with glutathione peroxidase-like and chain-breaking antioxidant activity

Catalytic Antioxidants: Regenerable Tellurium Analogues of Vitamin E

Singh, Vijay; Poon, Jia-fei; Engman, Lars

Part of Organic Letters, p. 6274-6277, 2013.

DOI for Catalytic Antioxidants: Regenerable Tellurium Analogues of Vitamin E

Ebsulfur is a benzisothiazolone cytocidal inhibitor targeting the trypanothione reductase of Trypanosoma brucei

Lu, Jun; Vodnala, Suman K.; Gustavsson, Anna-Lena; Gustafsson, Tomas N et al.

Part of Journal of Biological Chemistry, p. 27456-27468, 2013.

DOI for Ebsulfur is a benzisothiazolone cytocidal inhibitor targeting the trypanothione reductase of Trypanosoma brucei

In Search of Catalytic Antioxidants-(Alkyltelluro)phenols, (Alkyltelluro)resorcinols, and Bis(alkyltelluro)phenols

Poon, Jia-fei; Singh, Vijay P.; Engman, Lars

Part of Journal of Organic Chemistry, p. 6008-6015, 2013.

DOI for In Search of Catalytic Antioxidants-(Alkyltelluro)phenols, (Alkyltelluro)resorcinols, and Bis(alkyltelluro)phenols

Multi-faceted reactivity of alkyltellurophenols towards peroxyl radicals: Catalytic antioxidant versus thiol-depletion effect

Amorati, Riccardo; Valgimigli, Luca; Dinér, Peter; Bakhtiari, Khadijeh et al.

Part of Chemistry - A European Journal, p. 7510-7522, 2013.

DOI for Multi-faceted reactivity of alkyltellurophenols towards peroxyl radicals: Catalytic antioxidant versus thiol-depletion effect

Inhibition of Bacterial Thioredoxin Reductase: An Antibiotic Mechanism Targetting Bacteria Lacking Glutathione

Lu, Jun; Vlamis-Gardikas, Alexios; Kandasamy, Karuppasamy; Zhao, Rong et al.

Part of The FASEB Journal, p. 1394-1403, 2013.

DOI for Inhibition of Bacterial Thioredoxin Reductase: An Antibiotic Mechanism Targetting Bacteria Lacking Glutathione

Turning Pyridoxine into a Catalytic Chain-Breaking and Hydroperoxide-Decomposing Antioxidant

Singh, Vijay P.; Poon, Jia-fei; Engman, Lars

Part of Journal of Organic Chemistry, p. 1478-1487, 2013.

DOI for Turning Pyridoxine into a Catalytic Chain-Breaking and Hydroperoxide-Decomposing Antioxidant

Palladium-catalyzed Sonogashira cross-coupling of organic tellurides with alkynes

Kawaguchi, Shin-ichi; Srivastava, Puneet; Engman, Lars

Part of Tetrahedron Letters, p. 4120-4122, 2011.

DOI for Palladium-catalyzed Sonogashira cross-coupling of organic tellurides with alkynes

Long-lasting Antioxidant Protection: A Regenerable BHA-Analogue

Johansson, Henrik; Shanks, David; Engman, Lars; Amorati, Riccardo et al.

Part of Journal of Organic Chemistry, p. 7535-7541, 2010.

DOI for Long-lasting Antioxidant Protection: A Regenerable BHA-Analogue

Extraction of Antioxidants from Spruce (Picea abies) Bark using Eco-Friendly Solvents

Co, Michelle; Fagerlund, Amelie; Engman, Lars; Sunnerheim, Kerstin et al.

Part of Phytochemical Analysis, p. 1-11, 2012.

DOI for Extraction of Antioxidants from Spruce (Picea abies) Bark using Eco-Friendly Solvents

Organochalcogen Substituents in Phenolic Antioxidants

Amorati, Riccardo; Pedulli, Gian Franco; Valgimigli, Luca; Johansson, Henrik et al.

Part of Organic Letters, p. 2326-2329, 2010.

DOI for Organochalcogen Substituents in Phenolic Antioxidants

Antioxidants for use in therapy. 

Engman, Lars; Johansson, Henrik

2009.

Bacterial Thioredoxin Reductase Inhibitors and Methods for Use Thereof

Engman, Lars; Holmgren, Arne; Vlamis-Gardikas, A.; Zhao, R. et al.

2009.

Compositions and Methods.

Engman, Lars

2009.

Differential inhibition of high and low M_r thioredoxin reductases of parasites by organotelluriums supports the concept that low M_r thioredoxin reductases are good drug targets

McMillan, P. J; Patzewitz, E. M; Young, S.E.; Westrop, G. D. et al.

Part of Parasitology, p. 27-33, 2009.

DOI for Differential inhibition of high and low M_r thioredoxin reductases of parasites by organotelluriums supports the concept that low M_r thioredoxin reductases are good drug targets

Exploring a synthetic organoselenium compound for antioxidant pharmacotherapy: toxicity and effects on ROS-production

Johansson, Henrik; Svartström, Olof; Phadnis, Prasad; Engman, Lars et al.

Part of Bioorganic & Medicinal Chemistry, p. 1783-1788, 2010.

DOI for Exploring a synthetic organoselenium compound for antioxidant pharmacotherapy: toxicity and effects on ROS-production

A radical cyclization route to cyclic imines

Srivastava, Puneet; Engman, Lars

Part of Tetrahedron Letters, p. 1149-1151, 2010.

DOI for A radical cyclization route to cyclic imines

Catalytic chain-breaking pyridinol antioxidants

Kumar, Sangit; Johansson, Henrik; Kanda, Takahiro; Engman, Lars et al.

Part of Journal of Organic Chemistry, p. 716-725, 2010.

DOI for Catalytic chain-breaking pyridinol antioxidants

Catalytic Chain-breaking Pyridinol Antioxidants

Kumar, Sangit; Johansson, Henrik; Kanda, Takahiro; Engman, Lars et al.

Part of Organic Letters, p. 4895-4898, 2008.

DOI for Catalytic Chain-breaking Pyridinol Antioxidants

Compositions and Methods

Engman, Lars

2008.

Differential inhibition of high and low M_r thioredoxin reductases of parasites by organotelluriums supports the concept that low M_r thioredoxin reductases are good drug targets

Engman, Lars; McMillan, P; Patzewitz, E. M.; Young, S.E. et al.

Part of Parasitology, p. 27-33, 2009.

Thioredoxin Reductase and Cancer Cell Growth Inhibition by Organotellurium Compounds that could be Selectively Incorporated into Tumor Cells

Engman, Lars; Al-Maharik, Nawaf; McNaughton, Michael; Birmingham, A et al.

Part of Bioorganic & Medicinal Chemistry, p. 5091-5100, 2003.

DOI for Thioredoxin Reductase and Cancer Cell Growth Inhibition by Organotellurium Compounds that could be Selectively Incorporated into Tumor Cells

The Antioxidant Profile of 2,3-Dihydrobenzo[b]furan-5-ol and its 1-Thio, 1-Seleno, and 1-Telluro Analogues

Malmström, Jonas; Jonsson, Mats; Cotgreave, Ian A.; Hammarström, Leif et al.

Part of Journal of the American Chemical Society, p. 3434-3440, 2001.

Bacterial Thioredoxin Reductase Inhibitors and Methods for Use Thereof

Holmgren, Arne; Lu, Jun; Vlamis-Gardikas, Alexios; Zhao, Rong et al.

2007.

Antioxidant Profile of Ethoxyquin and Some of Its S, Se, and Te Analogues

Kumar, Sangit; Engman, Lars; Valgimigli, Luca; Amorati, Richard et al.

Part of Journal of Organic Chemistry, p. 6046-6055, 2007.

DOI for Antioxidant Profile of Ethoxyquin and Some of Its S, Se, and Te Analogues

Regenerable Chain-Breaking 2,3-Dihydrobenzo[b]selenophene-5-ol Antioxidants

Kumar, Sangit; Johansson, Henrik; Engman, Lars; Valgimigli, Luca et al.

Part of Journal of Organic Chemistry, p. 2583-2595, 2007.

DOI for Regenerable Chain-Breaking 2,3-Dihydrobenzo[b]selenophene-5-ol Antioxidants

Design principles for a-tocopherol analogues

Shanks, David; Frisell, Håkan; Ottosson, Henrik; Engman, Lars

Part of Organic and biomolecular chemistry, p. 846-852, 2006.

DOI for Design principles for a-tocopherol analogues

Microwave-Assisted Copper-Catalyzed Preparation of Diaryl Chalcogenides

Kumar, Sangit; Engman, Lars

Part of J. Org. Chem., p. 5400-5403, 2006.

DOI for Microwave-Assisted Copper-Catalyzed Preparation of Diaryl Chalcogenides

Probing the antioxidative properties of combinations of an organotellurium compound, BHT and thiol in oil

Shanks, David; Engman, Lars; Pach, Mayte; Norrby, Thomas

Part of Lubrication Science, p. 87-94, 2006.

DOI for Probing the antioxidative properties of combinations of an organotellurium compound, BHT and thiol in oil

Organoselenium-Substituted Poly(p-phenylenevinylene)

Stuhr-Hansen, Nicolai; Beckers, Edwin H. A.; Engman, Lars; Janssen, René A.J.

Part of Heteroatom Chemistry, p. 656-662, 2005.

DOI for Organoselenium-Substituted Poly(p-phenylenevinylene)

Improved Antioxidant Formulations for Polymeric Materials: Synergistic Protective Effects in Combinations of Organotellurium Compounds with Conventional Phenolic Antioxidants or Thiols

Shanks, David; Al-Maharik, Nawaf; Malmström, Jonas; Engman, Lars et al.

Part of Polymer degradation and stability, p. 261-271, 2003.

DOI for Improved Antioxidant Formulations for Polymeric Materials: Synergistic Protective Effects in Combinations of Organotellurium Compounds with Conventional Phenolic Antioxidants or Thiols

Protective Effects of Synthetic and Naturally Occurring Antioxidants in Pulp Products

Fagerlund, Amelie; Shanks, David; Sunnerheim, Kerstin; Engman, Lars et al.

Part of Nordic Pulp & Paper Research Journal, p. 176-181, 2003.

DOI for Protective Effects of Synthetic and Naturally Occurring Antioxidants in Pulp Products

An organoiron approach to thyroid hormone analogues

Smirnova, Joulia; Engman, Lars; Andersson, Carl-Magnus; Malm, Johan

Part of Journal of Organo metallic Chemistry, p. 1784-1792, 2005.

DOI for An organoiron approach to thyroid hormone analogues