Publication list

Researcher ID LogoORCID iD icon

Flag SwedenUppsala University

Uppsala, Sweden

47)

Y. Fareed, D. Braun, M. Flasch, D. Globisch, B. Warth

Exposome 2022, 2, osac008.

"A broad, exposome-type evaluation of xenobiotic phase II biotransformation in human biofluids by LC-MS/MS"

46)

N. Nyström, S. Prast-Nielsen, M.S.P. Correia, D. Globisch, L. Engstrand, I. Schuppe Koistinen, J. Halfvarson

J Crohns Colitis 2022, accepted; (doi: 10.1093/ecco-jcc/jjac149).

"Mucosal and plasma metabolomes in new-onset paediatric inflammatory bowel disease: correlations with disease characteristics and plasma inflammation protein markers"

45)

X. Zhang, E. Akcan, M.S.P. Correia, N. Rameika, S. Kundu, I. Stoimenov, V. Rendo, A.U. Eriksson, M. Haraldsson, D. Globisch, T. Sjöblom

Biochem. Pharmacol. 2022, 203, 115184.

"Enhanced cytotoxicity of a novel family of ATPase inhibitors in colorectal cancer cells with high NAT2 activity"

44)

T. Vallianatou, N.B. Bèchet, M.S.P. Correia, I. Lundgaard, D. Globisch

Metabolites 2022, 12, 21.

"Regional brain analysis of modified amino acids and dipeptides during the sleep/wake cycle"

43)

W. Lin, L.P. Conway, M. Vujasinovic, J.-M. Löhr, D. Globisch

Angew. Chem. Int. Ed. 2021, 60, 23232-23240.

"Chemoselective and highly sensitive quantification of gut microbiome and human metabolites"

G)

D. Globisch

Research Features 2021

"Analysing gut microbiome metabolites to detect disease"

42)

M.S.P. Correia, B. Thapa, M. Vujasinovic, J.-M. Löhr, D. Globisch

RSC Adv. 2021, 11, 34788-34794. Featured in the Emerging Investigators Series.

"Investigation of the individual human sulfatome in plasma and urine samples reveals an age-dependency"

41)

W. Lin, Z. Yang, A. Kaur, A. Block, M. Vujasinovic, J.-M. Löhr, D. Globisch

RSC Chem. Biol. 2021, 2, 1479-1483.

"Squaric acid as a new chemoselective moiety for mass spectrometry-based metabolomics analysis of amines"

40)

T. Vallianatou, W. Lin, N.B. Bèchet, M.S.P. Correia, N.C. Shanbhag, I. Lundgaard, D. Globisch

J. Cereb. Blood Flow Metab. 2021, 41, 12.

"Differential regulation of oxidative stress, microbiota-derived, and energy metabolites in the mouse brain during sleep"

39)

E. Joffré, X. Xiao, M.S.P. Correia, I. Nookaew, S. Sasse, D. Globisch, B. Zhu, Å. Sjöling

Microbiol. Spectr. 2022, accepted.

"Analysis of Growth Phases of Enterotoxigenic Escherichia coli Reveals a Distinct Transition Phase before Entry into Early Stationary Phase with Shifts in Tryptophan, Fucose, and Putrescine Metabolism and Degradation of Neurotransmitter Precursors"

38)

S. Kundu, M.A. Ali, N. Handin, L.P. Conway, V. Rendo, P. Artursson, L. He, D. Globisch, T. Sjöblom

J. Exp. Clin. Cancer Res. 2021, 40, 225.

"Common and Mutation Specific Phenotypes of KRAS and BRAF Mutations in Colorectal Cancer Cells Revealed by Integrative-Omics Analysis"

37)

A. Jain, M.S.P. Correia, H. Meistermann, M. Vujasinovic, J.-M. Löhr, D. Globisch

J. Pharm. Biomed. Anal. 2021, 195, 113818. Invited for the Special Issue: "Microbiota: An analytical perspective".

"Comparison of two arylsulfatases for targeted mass spectrometric analysis of microbiota-derived metabolites"

36)

M.S.P. Correia, W. Lin, A. J. Aria, A. Jain, D. Globisch

Metabolites 2020, 10, 415.

"Rapid preparation of a large sulfated metabolite library for structure validation in human samples"

35)

M.S.P. Correia+, A. Jain+, W. Alotaibi, P. Young Tie Yang, A. Rodriguez-Mateos,* D. Globisch*

Free Radic. Biol. Med. 2020, 160, 745-754.

"Comparative dietary sulfated metabolome analysis reveals unknown metabolic interactions of the gut microbiome and the human host"

34)

L. P. Conway+, V. Rendo+, M.S.P. Correia, I.A. Bergdahl, T. Sjöblom*, D. Globisch*

Angew. Chem. Int. Ed. 2020, 59, 14342-14346.

"Unexpected Acetylation of Endogenous Aliphatic Amines by Arylamine N‐Acetyltransferase NAT2"

33)

E. Marklund, B. van Oosten, G. Mao, E. Amselem, K. Kipper, A. Sabantsev, A. Emmerich, D. Globisch, X. Zhen, L. C. Lehmann, O. G. Berg, M. Johansson, J. Elf, S. Deindl

Nature 2020, 583, 858-861.

DNA surface exploration and operator bypassing during target search

32)

M. Nainytè, F. Müller, G. Ganazzoli, C.-Y. Chan, A. Crisp, D. Globisch, T. Carell

Chem. Eur. J. 2020, 26, 14856-14860.

Amino Acid Modified RNA Bases as Building Blocks of an Early Earth RNA-Peptide World

31)

W. Lin, L. P. Conway, A. Block, G. Sommi, M. Vujasinovic, J.-M. Löhr, D. Globisch

Analyst 2020, 145, 3822-3831. Featured in the Analyst Emerging Investigators Series.

Sensitive mass spectrometric analysis of carbonyl metabolites in human urine and fecal samples using chemoselective modification

F)

D. Globisch

EU Research 2020.

Intestinal microbiota metabolism - biomarker discovery for pancreatic cancer

30)

L. P. Conway, N. Garg, W. Lin, M. Vujasinovic, J.-M. Löhr, D. Globisch

Chem. Comm. 201955, 9080-9083.

Chemoselective Probe for Detailed Analysis of Ketones and Aldehydes Produced by Gut Microbiota in Human Samples

Table Of Contents ImageCover Image

29)

M. S. P. Correia, M. Rao, C. Ballet, D. Globisch

ChemBioChem 201920, 1678-1683. Featured in the ChemBioTalents Issue.

Enzymatic and mass spectrometric analysis for selective identification of glucuronidated metabolites in human samples

Table Of Contents Image

E)

L. P. Conway, M. S. P. Correia, D. Globisch

GIT Laboratory Journal  2019.

Hunting Gut Microbiota Metabolites - Elucidating the Metabolic Interplay with Their Human Host

28)

M. S. P. Correia+, C. Ballet+, H. Meistermann,  L. P. Conway, D. Globisch

Bioorg. Med. Chem. 201927, 955-962.

Comprehensive kinetic and substrate specificity analysis of an arylsulfatase from Helix pomatia using mass spectrometry


Table Of Contents Image

27)

N. Garg+, L. P. Conway+, C. Ballet, M. S. P. Correia, F. K. S. Olsson, M. Vujasinovic, J.-M. Löhr, D. Globisch

Angew. Chem. Int. Ed. 201857, 13805-13809​.

Chemoselective Probe Harboring a Unique Bioorthogonal Cleavage Site for Investigation of Gut Microbiota Metabolism

Table Of Contents Image

26)

C. Ballet+, M. S. P. Correia+, L. P. Conway, T. L. Locher, L. C. Lehmann, N. Garg, M. Vujasinovic, S. Deindl, J.-M. Löhr, D. Globisch

Chem. Sci. 20189, 6233-6239.

New enzymatic and mass spectrometric methodology for the selective investigation of gut microbiota-derived metabolites

Table Of Contents Image

25)

R. J. Shirey, D. Globisch, L. M. Eubanks, M. S. Hixon, K. D. Janda

ACS Infect. Dis. 2018, 4, 1423-1431.​

Non-Invasive Urine Biomarker Lateral Flow Immunoassay for Monitoring Active Onchocerciasis

Cover Image

24)

N. Garg, A. Hansson, H. K. Knych, S. D. Stanley, M. Thevis, U. Bondesson, M. Hedeland, D. Globisch

Org. Biomol. Chem. 2018, 16, 698-702.

Structural elucidation of major selective androgen receptor modulator (SARM) metabolites for doping control

Table Of Contents Image

Flag USAThe Scripps Research Institute

La Jolla, CA, USA 

23)

D. Globisch*, L. M. Eubanks, R. J. Shirey, K. M. Pfarr, S. Wanji, A. Y. Debrah, A. Hoerauf, K. D. Janda

Bioorg. Med. Chem. Lett. 2017, 27, 3436-3440.

"Validation of Onchocerciasis Biomarker N-Acetyltyramine-O-glucuronide (NATOG)"

22)

K. Tsuchikama, M. Gooyit, T. L. Harris, J. Zhu, D. Globisch, G. F. Kaufmann, K. D. Janda

Angew. Chem. Int. Ed. 2016, 55, 4002-4006.

Glycation Reactivity of a Quorum-Sensing Signaling Molecule

21)

D. Globisch, S. Specht, K. M. Pfarr, Lisa M. Eubanks, A. Hoerauf, K. D. Janda

Bioorg. Med. Chem. Lett. 2015, 25, 5804-5807.

Litomosoides sigmodontis: A Jird Urine Metabolome Study

20)

X. Cai, D. Globisch, P. Thompson, J. Lin, D. Toader, N. Dimasi, C. Gao, K. D. Janda

Tetrahedron Lett. 2015, 56, 3172-3175.

A chemoenzymatic approach toward the preparation of site-specific antibody–drug conjugates

19)

J. W. Lockner, L. Eubanks, J. M. Lively, J. Choi, J. E. Schlosburg, K. C. Collins, D. Globisch, R. J. Rosenfeld-Gunn, I. A. Wilson, K. D. Janda

Mol. Pharmacol. 2015, 12, 653-662.

Flagellin Protein as Carrier and Adjuvant in a Cocaine Vaccine

18)

J. Zhu, M. S. Hixon, D. Globisch, G. F. Kaufmann, K. D. Janda

J. Am. Chem. Soc. 2013, 135, 7827-7830.

Mechanistic insights into the LsrK kinase required for autoinducer-2 quorum sensing activation

17)

D. Globisch, A. Y. Moreno, M. S. Hixon, A. A. K. Nunes, J. R. Denery, S. Specht, A. Hoerauf, K. D. Janda

Proc. Natl. Acad. Sci. U S A. 2013, 110, 4218-4223.

Onchocerca volvulus-neurotransmitter tyramine is a biomarker for river blindness

Selected as Cover Image: Proc. Natl. Acad. Sci. U S A. 2013, 110 (11).

Research Highlight in Nature 2013, 495, 8; News of the Week in Chem. & Eng. News 2013, 91, 11; Science Now in Science February 2013.

Cover Image

16)

D. Globisch, C. A. Lowery, K. C. McCague, K. D. Janda

Angew. Chem. Int. Ed. 2012, 51, 4204-4208; Angew. Chem. 2012, 124, 4280-4284.

Uncharacterized 4,5-Dihydroxy-2,3-Pentanedione (DPD) Molecules Revealed Through NMR Spectroscopy: Implications for a Greater Signaling Diversity in Bacterial Species

  • Selected as Inside Back Cover: Angew. Chem. Int. Ed. 2012, 51, 4239.
  • Very Important Paper; Spotlight in ACS Chem. Biol. 2012, 7, 789-790; Highlight in Angew. Chem. Int. Ed. 2012, 51, 6314-6315.

Cover Image

15)

J. S. Zakhari, I. Kinoyama, M. S. Hixon, A. Di Mola, D. Globisch, K. D. Janda

Bioorg. Med. Chem. 2011, 19, 6203-6209.

Formulating a new basis for the treatment against botulinum neurotoxin intoxication: 3,4‑diaminopyridine prodrug design and characterization

Ludwig-Maximilians-University MunichFlag Germany

Munich, Germany 

14)

C. Brandmayr, M. Wagner, T. Brückl, D. Globisch, D. Pearson, A. C. Kneuttinger, V. Reiter, A. Hienzsch, S. Koch, I. Thoma, P. Thumbs, S. Michalakis, M. Müller, M. Biel, T. Carell

Angew. Chem. Int. Ed. 2012, 51, 11162-11165; Angew. Chem. 2012, 124, 11324-11328.

Isotope-based analysis of modified tRNA nucleosides correlates modification density with translational efficiency

13)

T. F. Kraus+, D. Globisch+, M. Wagner, S. Eigenbrod, D. Widmann, M. Münzel, M. Müller, T. Pfaffeneder, B. Hackner, W. Feiden, U. Schüller, T. Carell, H. A. Kretzschmar

Int. J. Cancer 2012, 131, 1577-1590.

Low values of 5-hydroxymethylcytosine (5hmC), the "sixth base", are associated with anaplasia in human brain tumors

+: These authors contributed equally

12)

V. Reiter, D. Matschkal, M. Wagner, D. Globisch, A. Kneuttinger, M. Müller, T. Carell

Nucleic Acids Res. 2012, 40, 6235-6240.

The CDK5 repressor CDK5RAP1 is a methylthiotransferase acting on nuclear and mitochondrial RNA

11)

D. Globisch, D. Pearson, A. Hienzsch, T. Brückl, M. Wagner, I. Thoma, P. Thumbs, V. Reiter, A. C. Kneuttinger, M. Müller, S. A. Sieber, T. Carell

Angew. Chem. Int. Ed. 2011, 50, 9739-9742; Angew. Chem. 2011, 123, 9913-9916.

Systems-Based Analysis of Modified tRNA Bases

  • Selected as Hot Paper.

10)

M. Münzel+, D. Globisch+, T. Carell

Angew. Chem. Int. Ed. 2011, 50, 6460-6468; Angew. Chem. 2011, 123, 6588-6596.

5-Hydroxymethylcytosine, the Sixth Base of the Genome” (Minireview)

+: These authors contributed equally

9)

M. Münzel, C. Szeibert, A. F. Glas, D. Globisch, T. Carell

J. Am. Chem. Soc. 2011, 133, 5186-5189.

Discovery and Synthesis of a new UV-induced Intrastrand C(4-8)G Photolesion

8)

D. Pearson, A. Hienzsch, M. Wagner, D. Globisch, V. Reiter, D. Özden, T. Carell

Chem. Comm. 2011, 47, 5196-5198.

LC-MS based quantification of 2′-ribosylated nucleosides Ar(p) and Gr(p) in tRNA

7)

D. Globisch+, M. Münzel+, M. Müller, S. Michalakis, M. Wagner, S. Koch, T. Brückl, M. Biel, T. Carell

PLoS One 2010, 5, e15367.

> 616 citations

Tissue Distribution of 5-Hydroxymethylcytosine and Search for Active Demethylation Intermediates

+: These authors contributed equally

6)

M. Münzel, D. Globisch, C. Trindler, T. Carell

Org. Lett. 2010, 12, 5671-5673.

Efficient Synthesis of 5-Hydroxymethylcytosine Containing DNA

5)

M. Münzel+, D. Globisch+, T. Brückl, M. Wagner, V. Welzmiller, S. Michalakis, M. Müller, M. Biel, T. Carell

Angew. Chem. Int. Ed. 2010, 49, 5375-5377; Angew. Chem. 2010, 122, 5503-5505.

Quantification of the sixth DNA base hydroxymethylcytosine in the brain

  • Highlight in Chem. Eng. News 2010, 88 (No 27), 24; Selected as Hot Paper.

+: These authors contributed equally

4)

T. Brückl+, D. Globisch+, M. Wagner, M. Müller, T. Carell

Angew. Chem. Int. Ed. 2009, 48, 7932-7934; Angew. Chem. 2009, 121, 8074-8077.

Parallel Isotope-Based Quantification of Modified tRNA Nucleosides

  • Highlight in Chem. Eng. News 2009, 87 (No 38), 35; Selected as Hot Paper.

+: These authors contributed equally

University of Southern DenmarkFlag Denmark

Odense, Denmark 

3)

Y. M. Loksha, D. Globisch, R. Loddo, G. Collu, P. La Colla, E. B. Pedersen

ChemMedChem 2010, 5, 1847-1849.

A Novel Synthetic Route for the Anti-HIV Drug MC-1220 and its Analogues

2)

D. Globisch, N. Bomholt, V. V. Filichev, E. B. Pedersen

Helv. Chim. Acta 2008, 91, 805-818.

Stability of Hoogsteen Type triplexes – Electrostatic attraction between duplex backbone and TFO using an intercalating conjugate

1)

Y. M. Loksha, D. Globisch, E. B. Pedersen, P. La Colla, G. Collu, R. Loddo

J. Heterocycl. Chem. 2008, 45, 1161-1166.

Synthesis and Anti-HIV-1 Evaluation of 1,5-Disubstituted Pyrimidine-2,4-diones

Conference Articles 

D)

N. Rameika, X. Zhang, V. Rendo, S. Kundu, D. Globisch, M.S.P. Correia, I. Stoimenov, T. Sjöblom

Ann. Oncol. 202233, 4, Page S303.

P-150 Targeting loss of heterozygosity in colorectal cancer

C)

G.M. Ferri, C.M. Harvey, D. Globisch, K.D. Janda, K.N. Allen

FASEB J. 201832 :674.16.

Using M. marinum T6PP as a Model for M. tuberculosis Inhibitor Design

B)

C. Harvey, C. Liu, D. Globisch, K.D. Janda, D. Dunaway-Mariano, K. Allen

FASEB J. 201731 :923.5.

Trehalose-6-Phosphate Phosphatase Structure and Inhibitor Design

A)

E. B. Pedersen, A.M.A. Osman, D. Globisch, M. Paramasiva, S. Cogoi, N. Bomholt, P.T. Jørgensen, L.E. Xodo, V.V. Filichev

Nucleic Acids Symp Ser (Oxf) 200852 37-38.

Triplex glue by synthesizing conjugated flexible intercalators

Last modified: 2022-10-18