Jonas Bergquist's group

Within our field different subject disciplines meet to jointly develop tomorrow's analytical technologies to gain new knowledge of chemical and biological processes in diseases. My research has mainly focused on understanding what happens in patients suffering from various neurodegenerative diseases such as Parkinson's, Alzheimer's, amyotrophic lateral sclerosis (ALS) and multiple sclerosis (MS). We study these phenomena, in-situ or ex-vivo, in  brain tissue and cerebrospinal fluid.

The step from clinical neuroscience to  analytical chemistry is not so great, especially within the field of neurochemistry, where both disciplines are of great importance. The kind of analysis which my research group is conducting involves methods to measure substances that can act as biomarkers for early diagnosis and contribute to the understanding of what initiates the disease process. We measure not only the individual substances but also seek patterns and monitor how they change during illness. Our specialty is the analysis of cerebrospinal fluid and its chemical composition.