Publikationer

Improved molecular recognition of Carbonic Anhydrase IX by polypeptide conjugation to acetazolamide

Yang, Jie; Koruza, Katarina; Fisher, Zoë; Knecht, Wolfgang et al.

Ingår i Bioorganic & Medicinal Chemistry, s. 5838-5848, 2017.

DOI för Improved molecular recognition of Carbonic Anhydrase IX by polypeptide conjugation to acetazolamide

High-affinity recognition of the human C-reactive protein independent of phosphocholine

Yang, Jie; Gustavsson, Anna-Lena; Haraldsson, Martin; Karlsson, Göran et al.

Ingår i Organic and biomolecular chemistry, s. 4644-4654, 2017.

DOI för High-affinity recognition of the human C-reactive protein independent of phosphocholine

Conjugation of a Dipicolyl Chelate to Polypeptide Conjugates Increases Binding Affinities for Human Serum Albumin and Survival Times in Human Serum

Balliu, Aleksandra; Baltzer, Lars

Ingår i ChemBioChem (Print), s. 1408-1414, 2017.

DOI för Conjugation of a Dipicolyl Chelate to Polypeptide Conjugates Increases Binding Affinities for Human Serum Albumin and Survival Times in Human Serum

Exploring Non-obvious Hydrophobic Binding Pockets on Protein Surfaces: Increasing Affinities in Peptide–Protein Interactions

Balliu, Aleksandra; Baltzer, Lars

Ingår i ChemBioChem (Print), s. 1396-1407, 2017.

DOI för Exploring Non-obvious Hydrophobic Binding Pockets on Protein Surfaces: Increasing Affinities in Peptide–Protein Interactions

Improving the Diagnosis and Management of Neuroendocrine Tumors: Utilizing New Advances in Biomarker and Molecular Imaging Science

Giandomenico, Valeria; Modlin, Irvin M.; Pontén, Fredrik; Nilsson, Mats et al.

Ingår i Neuroendocrinology, s. 16-30, 2013.

DOI för Improving the Diagnosis and Management of Neuroendocrine Tumors: Utilizing New Advances in Biomarker and Molecular Imaging Science

Intrinsically unstructured proteins by designelectrostatic interactions can control binding, folding, and function of a helix-loop-helix heterodimer

Rydberg, Johan; Baltzer, Lars; Sarojini, Vijayalekshmi

Ingår i Journal of Peptide Science, s. 461-469, 2013.

DOI för Intrinsically unstructured proteins by designelectrostatic interactions can control binding, folding, and function of a helix-loop-helix heterodimer

Designed protein binders in combination with nanocrystalline diamond for use in high-sensitivity biosensors

Fromell, Karin; Forsberg, Pontus; Karlsson, Mikael; Larsson, Karin et al.

Ingår i Analytical and Bioanalytical Chemistry, s. 1643-1651, 2012.

DOI för Designed protein binders in combination with nanocrystalline diamond for use in high-sensitivity biosensors

Specific functionalization of CTAB stabilized anisotropic gold nanoparticles with polypeptides for folding-mediated self-assembly

Wang, Yusong; Aili, Daniel; Selegard, Robert; Tay, Yeeyan et al.

Ingår i Journal of Materials Chemistry, s. 20368-20373, 2012.

DOI för Specific functionalization of CTAB stabilized anisotropic gold nanoparticles with polypeptides for folding-mediated self-assembly

A synthetic polypeptide conjugate from a 42-residue polypeptide and salicylhydroxamic acid binds human myeloperoxidase with high affinity

Sun, Xiaojiao; Yang, Jie; Norberg, Thomas; Baltzer, Lars

Ingår i Journal of Peptide Science, s. 731-739, 2012.

DOI för A synthetic polypeptide conjugate from a 42-residue polypeptide and salicylhydroxamic acid binds human myeloperoxidase with high affinity

Powerful binders for the D-dimer by conjugation of the GPRP peptide to polypeptides from a designed set: illustrating a general route to new binders for proteins

Ramapanicker, Ramesh; Sun, Xiaojiao; Viljanen, Johan; Baltzer, Lars

Ingår i Bioconjugate chemistry, s. 17-25, 2013.

DOI för Powerful binders for the D-dimer by conjugation of the GPRP peptide to polypeptides from a designed set: illustrating a general route to new binders for proteins

Polypeptide Folding-Mediated Tuning of the Optical and Structural Properties of Gold Nanoparticle Assemblies

Aili, Daniel; Gryko, Piotr; Sepulveda, Borja; Dick, John A. G. et al.

Ingår i Nano letters (Print), s. 5564-5573, 2011.

DOI för Polypeptide Folding-Mediated Tuning of the Optical and Structural Properties of Gold Nanoparticle Assemblies

Efficient formation of heterodimers from peptides and proteins using unsymmetrical polyfluorophenyl esters of dicarboxylic acids

Ślósarczyk, Adam T.; Baltzer, Lars

Ingår i Journal of Peptide Science, s. 261-269, 2012.

DOI för Efficient formation of heterodimers from peptides and proteins using unsymmetrical polyfluorophenyl esters of dicarboxylic acids

Mixed pentafluorophenyl and o-fluorophenyl esters of aliphatic dicarboxylic acids: efficient tools for peptide and protein conjugation

Ślósarczyk, Adam T.; Ramapanicker, Ramesh; Norberg, Thomas; Baltzer, Lars

Ingår i RSC Advances, s. 908-914, 2012.

DOI för Mixed pentafluorophenyl and o-fluorophenyl esters of aliphatic dicarboxylic acids: efficient tools for peptide and protein conjugation

The molecular recognition of phosphorylated proteins by designed polypeptides conjugated to a small molecule that binds phosphate

Ślósarczyk, Adam T.; Baltzer, Lars

Ingår i Organic and biomolecular chemistry, s. 7697-7704, 2011.

DOI för The molecular recognition of phosphorylated proteins by designed polypeptides conjugated to a small molecule that binds phosphate

Fungicidal activity of human lactoferrin-derived peptides based on the antimicrobial alpha beta region

Kondori, N.; Baltzer, Lars; Dolphin, G. T.; Mattsby-Baltzer, I.

Ingår i International Journal of Antimicrobial Agents, s. 51-57, 2011.

DOI för Fungicidal activity of human lactoferrin-derived peptides based on the antimicrobial alpha beta region

Colorimetric Protein Sensing by Controlled Assembly of Gold Nanoparticles Functionalized with Synthetic Receptors

Aili, Daniel; Selegard, Robert; Baltzer, Lars; Enander, Karin et al.

Ingår i Small, s. 2445-2452, 2009.

DOI för Colorimetric Protein Sensing by Controlled Assembly of Gold Nanoparticles Functionalized with Synthetic Receptors

A new assay design for clinical diagnostics based on alternative recognition elements

Albrecht, Christiane; Fechner, Peter; Honcharenko, Dmytro; Baltzer, Lars et al.

Ingår i Biosensors & bioelectronics, s. 2302-2308, 2010.

DOI för A new assay design for clinical diagnostics based on alternative recognition elements

Synthesis of C-11 linked active ester derivatives of vitamin D₃ and their conjugations to 42-residue helix–loop–helix peptides

Zhang, Qi; Norberg, Thomas; Bergquist, Jonas; Baltzer, Lars

Ingår i Tetrahedron, s. 4577-4586, 2010.

DOI för Synthesis of C-11 linked active ester derivatives of vitamin D₃ and their conjugations to 42-residue helix–loop–helix peptides

Self-assembly of fibers and nanorings from disulfide-linked helix-loop-helix polypeptides

Aili, Daniel; Tai, Feng-I; Enander, Karin; Baltzer, Lars et al.

Ingår i Angewandte Chemie International Edition, s. 5554-5556, 2008.

DOI för Self-assembly of fibers and nanorings from disulfide-linked helix-loop-helix polypeptides

Downsizing of Enzymes by Chemical Methods: Arginine Mimics with Low pK(a) Values Increase the Rates of Hydrolysis of RNA Model Compounds

Lindgren, N. Johan V.; Geiger, Lars; Schmuck, Carsten; Razkin, Jesus et al.

Ingår i Angewandte Chemie International Edition, s. 6722-6725, 2009.

DOI för Downsizing of Enzymes by Chemical Methods: Arginine Mimics with Low pK(a) Values Increase the Rates of Hydrolysis of RNA Model Compounds

Enhanced Complexity and Catalytic Efficiency in the Hydrolysis of Phosphate Diesters by Rationally Designed Helix–Loop–Helix Motifs

Razkin, Jesus; Lindgren, Johan; Nilsson, Helena; Baltzer, Lars

Ingår i ChemBioChem (Print), s. 1975-1984, 2008.

DOI för Enhanced Complexity and Catalytic Efficiency in the Hydrolysis of Phosphate Diesters by Rationally Designed Helix–Loop–Helix Motifs

Engineering and design: Expanding the protein world

Baltzer, Lars; DeGrado, W. F.

Ingår i Editorial overview Current Opinion of Structural Biology, s. 455-457, 2004.

Folding Induced Assembly of Polypeptide Decorated Gold Nanoparticles

Aili, Daniel; Enander, Karin; Rydberg, Johan; Nesterenko, Irina et al.

Ingår i Journal of the American Chemical Society, s. 5780-5788, 2008.

DOI för Folding Induced Assembly of Polypeptide Decorated Gold Nanoparticles

Catalysis of the Cleavage of Uridine 3‘-2,2,2-Trichloroethylphosphate by a Designed Helix−Loop−Helix Motif Peptide

Razkin, Jesus; Nilsson, Helena; Baltzer, Lars

Ingår i Journal of the American Chemical Society, s. 14752-14758, 2007.

DOI för Catalysis of the Cleavage of Uridine 3‘-2,2,2-Trichloroethylphosphate by a Designed Helix−Loop−Helix Motif Peptide

Polypeptide Conjugate Binders for Protein Recognition

Baltzer, Lars

Ingår i Topics in current chemistry, s. 89-106, 2007.

DOI för Polypeptide Conjugate Binders for Protein Recognition

Synthetic de novo designed polypeptides for control of nanoparticle assembly and biosensing

Aili, Daniel; Enander, Karin; Baltzer, Lars; Liedberg, Bo

Ingår i Biochemical Society Transactions, s. 532-534, 2007.

DOI för Synthetic de novo designed polypeptides for control of nanoparticle assembly and biosensing

A Novel ATR-FTIR Approach for Characterisation and Identification of Ex Situ Immobilised Species

Andersson, Per Ola; Lundquist, Margaretha; Tegler, Lotta; Börjegren, Susanne et al.

Ingår i ChemPhysChem, s. 712-722, 2007.

DOI för A Novel ATR-FTIR Approach for Characterisation and Identification of Ex Situ Immobilised Species

Combined Enzyme and Substrate Design: Grafting of a cooperative two-histidine catalytic motif into a protein targeted at the scissile bond in a designed ester substrate

Höst, Gunnar; Razkin, Jesus; Baltzer, Lars; Jonsson, Bengt-Harald

Ingår i ChemBioChem (Print), s. 1570-1576, 2007.

DOI för Combined Enzyme and Substrate Design: Grafting of a cooperative two-histidine catalytic motif into a protein targeted at the scissile bond in a designed ester substrate

Substrate Modulation of the Activity of an Artificial Nanoesterase Made of Peptide-Functionalized Gold Nanoparticles

Pengo, Paolo; Baltzer, Lars; Pasquato, Lucia; Scrimin, Paolo

Ingår i Angewandte Chemie International Edition, s. 400-404, 2007.

DOI för Substrate Modulation of the Activity of an Artificial Nanoesterase Made of Peptide-Functionalized Gold Nanoparticles

A new enzyme by rational design - the incorporation of a single His residue enables efficient thioester hydrolysis by human glutathione transferase A1-1

Hederos, Sofia; Broo, Kerstin; Jakobsson, Emma; Kleywegt, Gerard J et al.

Ingår i Proc. Nat. Acad. Sci., s. 13163-13167, 2004.

Incorporation of a single His residue by rational design enables thiol-ester hydrolysis by human glutathione transferase A1-1.

Hederos, Sofia; Broo, Kerstin S; Jakobsson, Emma; Kleywegt, Gerard J et al.

Ingår i Proc Natl Acad Sci U S A, s. 13163-7, 2004.

Alpha helix-inducing dimerization of synthetic polypeptide scaffolds on gold

Enander, Karin; Aili, D.; Baltzer, Lars; Lundström, I. et al.

Ingår i Langmuir, s. 2480-2487, 2005.

Model Systems

Scrimin, P.; Baltzer, Lars

Ingår i Editorial Overwiev, Current Opinion of Chemical Biology, s. 620-621, 2005.

A versatile polypeptide platform for intergrated recognition and reporting - affinity arrays for protein - ligand interaction analysis

Enander, Karin; Dolphin, G.T.; Liedberg, B.; Lundström, I. et al.

Ingår i Chem. Eur. J., s. 2375-2385, 2004.

Designed functionalized helix-loop-helix motifs that bind human Carbonic Anhydrase II- a new class of synthetic receptor molecules

Enander, Karin; Dolphin, G. T.; Baltzer, Lars

Ingår i J. Am. Chem. Soc., s. 4464-4465, 2004.

Twisting macromolecular chains - self-assembly of a chiral supermolecule from non-chiral polythiophene polyanions and random coil synthetic peptides

Peter, K.; Nilsson, R.; Rydberg, J.; Baltzer, Lars et al.

Ingår i Proc. Nat. Acad.Sci, s. 11197-11202, 2004.

A versatile polypeptide platform for integrated recognition and reporting - affinity arrays for protein-ligand interaction

Enander, Karin; Dolphin, Gunnar T.; Liedberg, Bo; Lundström, Ingemar et al.

Ingår i Chem. Eur. J., s. 2375-2385, 2004.

Acid base catalysis in designed polypeptides

Baltzer, Lars; Klinman, J.P.; Hynes, J.T.; Limbach, H-H.

Ingår i Handbook of Hydrogen Transfer, 2006.

Aggregation-Induced Folding of a de novo Designed Polypeptide Immobilized on Gold Nanoparticles

Aili, Daniel; Enander, Karin; Rydberg, Johan; Lundström, Ingemar et al.

Ingår i J. Am. Chem. Soc., s. 2194-2195, 2006.

Alpha helix-inducing dimerization of synthetic plypeptide scaffolds on gold

Enander, Karin; Aili, D.; Baltzer, Lars; Lundström, I. et al.

Ingår i Langmuir, s. 2480-2487, 2005.

Cooperative binding of human Carbonic Anhydrase II by functionalized folded polypeptide receptors

Andersson, Theresa; Lundquist, Martin; Dolphin, Gunnar T.; Enander, Karin et al.

Ingår i Chem. Biol., s. 1245-1252, 2005.

De novo Metallonucleases based on Helix-loop-helix Motifs

Rossi, Paola; Tecilla, Paolo; Baltzer, Lars; Scrimin, Paolo

Ingår i Chem. Eur. J., s. 4163-4170, 2004.

Designed, functionalized helix-loop-helix motifs that bind human Carbonic Anhydrase II - a new class of synthetic receptor molecules

Enander, Karin; Dolphin, Gunnar T.; Baltzer, Lars

Ingår i J. Am. Chem. Soc., s. 4464-4465, 2004.

Model Systems

Scrimin, Paolo; Baltzer, Lars

2005.

Nucleophile selectivity in the enzyme catalyzed acyl transfer reaction of a thiol ester

Hederos, Sofia; Baltzer, Lars

Ingår i Biopolymers, s. 292-299, 2005.

Twisting macromolecular chains-self-assembly of a chiral supermolecule from non-chiral polythiophene polyanions and random coil synthetic peptides

Peter, K.; Nilsson, R.; Rydberg, Johan; Baltzer, Lars et al.

Ingår i Proc. Nat. Acad. Sci., s. 11197-11202, 2004.