Metabolic and genetic engineering of cyanobacteria for enhanced H2 production
There is an urgent need to develop sustainable solutions to convert solar energy into energy carriers used in the society. In addition to solar cells generating electricity, there are several options to generate solar fuels with molecular hydrogen (H2) being an interesting and promising option. Native and engineered cyanobacteria are being used as model systems to examine, develop and demonstrate photobiological hydrogen production.
We are exploring cyanobacterial hydrogenases, how they function and are regulated. Moreover, we are addressing metabolic modulations and genetic engineering approches for enhanced H2 production. At present we focus on the introduction of custom-designed, non-native enzymes and complexes for enhanced hydrogen production in cyanobacteria. In addition, we specifically analyze electron transfer in the small subunit of a cyanobacterial hydrogenase.
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