Publications in Varghese Group
-
Dynamic covalent crosslinked hyaluronic acid hydrogels and nanomaterials for biomedical applications
Part of Biomaterials Science, p. 6399-6412, 2022.
DOI for Dynamic covalent crosslinked hyaluronic acid hydrogels and nanomaterials for biomedical applications Download full text (pdf) of Dynamic covalent crosslinked hyaluronic acid hydrogels and nanomaterials for biomedical applications
-
Heparin-Derived Theranostic Nanoprobes Overcome the Blood-Brain Barrier and Target Glioma in Murine Model
Part of Advanced Therapeutics, 2022.
DOI for Heparin-Derived Theranostic Nanoprobes Overcome the Blood-Brain Barrier and Target Glioma in Murine Model Download full text (pdf) of Heparin-Derived Theranostic Nanoprobes Overcome the Blood-Brain Barrier and Target Glioma in Murine Model
-
Interpenetrating gallol functionalized tissue adhesive hyaluronic acid hydrogel polarizes macrophages to an immunosuppressive phenotype
Part of Acta Biomaterialia, p. 36-48, 2022.
DOI for Interpenetrating gallol functionalized tissue adhesive hyaluronic acid hydrogel polarizes macrophages to an immunosuppressive phenotype Download full text (pdf) of Interpenetrating gallol functionalized tissue adhesive hyaluronic acid hydrogel polarizes macrophages to an immunosuppressive phenotype
-
An unexpected role of an extra phenolic hydroxyl on the chemical reactivity and bioactivity of catechol or gallol modified hyaluronic acid hydrogels
Part of Polymer Chemistry, p. 2987-2991, 2021.
DOI for An unexpected role of an extra phenolic hydroxyl on the chemical reactivity and bioactivity of catechol or gallol modified hyaluronic acid hydrogels Download full text (pdf) of An unexpected role of an extra phenolic hydroxyl on the chemical reactivity and bioactivity of catechol or gallol modified hyaluronic acid hydrogels
-
Discrepancies on the Role of Oxygen Gradient and Culture Condition on Mesenchymal Stem Cell Fate
Part of Advanced Healthcare Materials, 2021.
DOI for Discrepancies on the Role of Oxygen Gradient and Culture Condition on Mesenchymal Stem Cell Fate Download full text (pdf) of Discrepancies on the Role of Oxygen Gradient and Culture Condition on Mesenchymal Stem Cell Fate
-
Effect of the Addition Frequency of 5-Azacytidine in Both Micro- and Macroscale Cultures
Part of Cellular and Molecular Bioengineering, p. 121-130, 2021.
DOI for Effect of the Addition Frequency of 5-Azacytidine in Both Micro- and Macroscale Cultures Download full text (pdf) of Effect of the Addition Frequency of 5-Azacytidine in Both Micro- and Macroscale Cultures
-
Redox responsive Pluronic micelle mediated delivery of functional siRNA: a modular nano-assembly for targeted delivery
Part of Biomaterials Science, p. 3939-3944, 2021.
DOI for Redox responsive Pluronic micelle mediated delivery of functional siRNA: a modular nano-assembly for targeted delivery Download full text (pdf) of Redox responsive Pluronic micelle mediated delivery of functional siRNA: a modular nano-assembly for targeted delivery
-
PDMS leaching and its implications for on-chip studies focusing on bone regeneration applications
Part of Organs-on-a-Chip, 2020.
DOI for PDMS leaching and its implications for on-chip studies focusing on bone regeneration applications Download full text (pdf) of PDMS leaching and its implications for on-chip studies focusing on bone regeneration applications
-
4 '-Guanidinium-modified siRNA: a molecular tool to control RNAi activity through RISC priming and selective antisense strand loading
Part of Chemical Communications, p. 9112-9115, 2019.
DOI for 4 '-Guanidinium-modified siRNA: a molecular tool to control RNAi activity through RISC priming and selective antisense strand loading Download full text (pdf) of 4 '-Guanidinium-modified siRNA: a molecular tool to control RNAi activity through RISC priming and selective antisense strand loading
-
A turn-on fluorescent GFP chromophore analog for highly selective and efficient detection of H2S in aqueous and in living cells
Part of Sensors and actuators. B, Chemical, 2019.
-
An Unexpected Role of Hyaluronic Acid in Trafficking siRNA Across the Cellular Barrier: The First Biomimetic, Anionic, Non-Viral Transfection Method
Part of Angewandte Chemie International Edition, p. 2815-2819, 2019.
-
First Aldol Cross-Linked Hyaluronic Acid Hydrogel: Fast and Hydrolytically Stable Hydrogel with Tissue Adhesive Properties
Part of ACS Applied Materials and Interfaces, p. 38232-38239, 2019.
-
Impact of Hydrogel Cross-Linking Chemistry on the in Vitro and in VivoBioactivity of Recombinant Human Bone Morphogenetic Protein-2
Part of ACS Applied Bio Materials, 2019.
-
Influence of ions to modulate hydrazone and oxime reaction kinetics to obtain dynamically cross-linked hyaluronic acid hydrogels
Part of Polymer Chemistry, p. 4322-4327, 2019.
DOI for Influence of ions to modulate hydrazone and oxime reaction kinetics to obtain dynamically cross-linked hyaluronic acid hydrogels Download full text (pdf) of Influence of ions to modulate hydrazone and oxime reaction kinetics to obtain dynamically cross-linked hyaluronic acid hydrogels
-
Innovative strategy for 3D transfection of primary human stem cells with BMP-2 expressing plasmid DNA: A clinically translatable strategy for ex vivogene therapy
Part of International Journal of Molecular Sciences, 2019.
DOI for Innovative strategy for 3D transfection of primary human stem cells with BMP-2 expressing plasmid DNA: A clinically translatable strategy for ex vivogene therapy Download full text (pdf) of Innovative strategy for 3D transfection of primary human stem cells with BMP-2 expressing plasmid DNA: A clinically translatable strategy for ex vivogene therapy
-
Insights into siRNA Transfection in Suspension: Efficient Gene Silencing in Human Mesenchymal Stem Cells Encapsulated in Hyaluronic Acid Hydrogel
Part of Biomacromolecules, p. 1317-1324, 2019.
-
MicroRNA detection based on duplex-specific nuclease-assisted target recycling and gold nanoparticle/graphene oxide nanocomposite-mediated electrocatalytic amplification
Part of Biosensors & bioelectronics, p. 188-193, 2019.
-
Modulating thiol pKa promotes disulfide formation at physiological pH: An elegant strategy to design disulfide cross-linked hyaluronic acid hydrogels
Part of Biomacromolecules, p. 1412-1420, 2019.
-
Synthetic design of asymmetric miRNA with engineered 3′-overhang to improve strand selection
Part of Molecular Therapy - Nucleic Acids, p. 597-604, 2019.
DOI for Synthetic design of asymmetric miRNA with engineered 3′-overhang to improve strand selection Download full text (pdf) of Synthetic design of asymmetric miRNA with engineered 3′-overhang to improve strand selection
-
Saline Accelerates Oxime Reaction with Aldehyde and Keto Substrates at Physiological pH
Part of Scientific Reports, 2018.
DOI for Saline Accelerates Oxime Reaction with Aldehyde and Keto Substrates at Physiological pH Download full text (pdf) of Saline Accelerates Oxime Reaction with Aldehyde and Keto Substrates at Physiological pH
-
Thiazolidine chemistry revisited: a fast, efficient and stable click-type reaction at physiological pH
Part of Chemical Communications, p. 12507-12510, 2018.
DOI for Thiazolidine chemistry revisited: a fast, efficient and stable click-type reaction at physiological pH Download full text (pdf) of Thiazolidine chemistry revisited: a fast, efficient and stable click-type reaction at physiological pH
-
Host cell recruitment patterns by bone morphogenetic protein-2 releasing hyaluronic acid hydrogels in a mouse subcutaneous environment
Part of Regenerative Medicine, p. 525-539, 2017.
-
Injectable and thermoresponsive pericardial matrix derived conductive scaffold for cardiac tissue engineering
Part of RSC Advances, p. 31980-31988, 2017.
DOI for Injectable and thermoresponsive pericardial matrix derived conductive scaffold for cardiac tissue engineering Download full text (pdf) of Injectable and thermoresponsive pericardial matrix derived conductive scaffold for cardiac tissue engineering
-
Chondroitin sulfate derived theranostic nanoparticles for targeted drug delivery
Part of Biomaterials Science, p. 1310-1313, 2016.
DOI for Chondroitin sulfate derived theranostic nanoparticles for targeted drug delivery
-
Multifunctional Hyaluronic Acid and Chondroitin Sulfate Nanoparticles: Impact of Glycosaminoglycan Presentation on Receptor Mediated Cellular Uptake and Immune Activation
Part of ACS Applied Materials and Interfaces, p. 20614-20624, 2016.
-
2 '-N-Guanidino, 4 '-C-ethylene bridged thymidine (GENA-T) modified oligonucleotide exhibits triplex formation with excellent enzymatic stability
Part of RSC Advances, p. 12257-12260, 2015.
-
Chondroitin Sulfate-Coated DNA-Nanoplexes Enhance Transfection Efficiency by Controlling Plasmid Release from Endosomes: A New Insight into Modulating Nonviral Gene Transfection
Part of Advanced Functional Materials, p. 3907-3915, 2015.
-
Insights into the Mechanism and Catalysis of Oxime Coupling Chemistry at Physiological pH
Part of Chemistry - A European Journal, p. 5980-5985, 2015.
DOI for Insights into the Mechanism and Catalysis of Oxime Coupling Chemistry at Physiological pH
-
Cell type and transfection reagent-dependent effects on viability, cell content, cell cycle and inflammation of RNAi in human primary mesenchymal cells
Part of European Journal of Pharmaceutical Sciences, p. 35-44, 2014.
-
Host cell recruitment patterns by BMP-2 releasing hyaluronic acid gels in a mouse subcutaneous model
Part of Journal of Tissue Engineering and Regenerative Medicine, p. 65-65, 2014.
-
Mild and Efficient Strategy for Site-Selective Aldehyde Modification of Glycosaminoglycans: Tailoring Hydrogels with Tunable Release of Growth Factor
Part of Biomacromolecules, p. 2427-2432, 2013.
-
PLGA/PEG-hydrogel composite scaffolds with controllable mechanical properties
Part of Journal of Biomedical Materials Research. Part B - Applied biomaterials, p. 648-655, 2013.
DOI for PLGA/PEG-hydrogel composite scaffolds with controllable mechanical properties
-
Smart Design of Stable Extracellular Matrix Mimetic Hydrogel: Synthesis, Characterization, and In Vitro and In Vivo Evaluation for Tissue Engineering
Part of Advanced Functional Materials, p. 1273-1280, 2013.
-
Critical Assessment of rhBMP-2 Mediated Bone Induction: an In Vitro and In Vivo Evaluation
Part of Journal of Tissue Engineering and Regenerative Medicine, p. 39-39, 2012.
-
Critical assessment of rhBMP-2 mediated bone induction: An in vitro and in vivo evaluation.
Part of Journal of Controlled Release, p. 646-653, 2012.
DOI for Critical assessment of rhBMP-2 mediated bone induction: An in vitro and in vivo evaluation.
-
Injectable hyaluronic acid hydrogel for bone tissue engineering
Part of European Cells and Materials, p. 2-, 2012.
-
Keynote: Safe and efficient in-vivo gene gene transfer and silencing technologies using natural pathways
Part of Journal of Tissue Engineering and Regenerative Medicine, p. 190-190, 2012.
-
Minimally invasive mandibular bone augmentation using injectable hydrogels
Part of Journal of Tissue Engineering and Regenerative Medicine, p. s15-s23, 2012.
DOI for Minimally invasive mandibular bone augmentation using injectable hydrogels
-
Smart design of stable hydrazone crosslinked extracellular matrix mimetic hydrogel for tissue engineering application
Part of Journal of Tissue Engineering and Regenerative Medicine, p. 192-192, 2012.
-
Bone reservoir: Injectable hyaluronic acid hydrogel for minimal invasive bone augmentation
Part of Journal of Controlled Release, p. 232-240, 2011.
DOI for Bone reservoir: Injectable hyaluronic acid hydrogel for minimal invasive bone augmentation
-
Functionalization of Hyaluronic Acid with Chemoselective Groups via a Disulfide-Based Protection Strategy for In Situ Formation of Mechanically Stable Hydrogels
Part of Biomacromolecules, p. 2247-2254, 2010.
-
Modular approach to functional hyaluronic acid hydrogels using orthogonal chemical reactions
Part of Chemical Communications, p. 8368-8370, 2010.
DOI for Modular approach to functional hyaluronic acid hydrogels using orthogonal chemical reactions
-
Synthesis of Guanidinium-Modified Hyaluronic Acid Hydrogel
Part of Macromolecular rapid communications, p. 1175-1180, 2010.
DOI for Synthesis of Guanidinium-Modified Hyaluronic Acid Hydrogel
-
In Situ Cross-Linkable High Molecular Weight Hyaluronan−Bisphosphonate Conjugate for Localized Delivery and Cell-Specific Targeting: A Hydrogel Linked Prodrug Approach
Part of Journal of the American Chemical Society, p. 8781-8783, 2009.
-
Comparison of the RNase H Cleavage Kinetics and Blood Serum Stability of the North-Conformationally Constrained and 2‘-Alkoxy Modified Oligonucleotides
Part of Biochemistry, p. 5635-5646, 2007.
-
Conformationally Constrained 2'-N,4'-C-Ethylene-Bridged Thymidine (Aza-ENA-T): Synthesis, Structure, Physical, and Biochemical Studies of Aza-ENA-T-Modified Oligonucleotides
Part of Journal of the American Chemical Society, p. 15173-15187, 2006.
-
Synthesis and Structure of Novel Conformationally-constrained 1'2'-Azetidine-Fused Bicyclic Pyrimidine Nucleosides: Their Incorporation into Oligo-DNAs and the Thermal Stability of the Heteroduplexes
Part of Journal of Organic Chemistry, p. 299-314, 2006.
-
The chemical nature of the 2'-substituent in the pentose-sugar dictates the pseudoaromatic character of the nucleobase (pKa) in DNA/RNA.
Part of Org. Biomol. Chem., p. 1675-1686, 2006.
-
The chemical nature of the 2'-substituent in the pentosesugar dictates the pseudoaromatic character of the nucleobase (pKa) in DNA/RNA
Part of Org Biomol Chem, p. 1675-1686, 2006.
-
First Aldol-Crosslinked Hyaluronic Acid Hydrogel: Fast and Hydrolytically Stable Gel with Tissue Adhesive Properties
Part of Chemical Sciences Journal