Publikationer i Vargheses grupp
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Dynamic covalent crosslinked hyaluronic acid hydrogels and nanomaterials for biomedical applications
Ingår i Biomaterials Science, s. 6399-6412, 2022.
DOI för Dynamic covalent crosslinked hyaluronic acid hydrogels and nanomaterials for biomedical applications Ladda ner fulltext (pdf) av Dynamic covalent crosslinked hyaluronic acid hydrogels and nanomaterials for biomedical applications
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Heparin-Derived Theranostic Nanoprobes Overcome the Blood-Brain Barrier and Target Glioma in Murine Model
Ingår i Advanced Therapeutics, 2022.
DOI för Heparin-Derived Theranostic Nanoprobes Overcome the Blood-Brain Barrier and Target Glioma in Murine Model Ladda ner fulltext (pdf) av Heparin-Derived Theranostic Nanoprobes Overcome the Blood-Brain Barrier and Target Glioma in Murine Model
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Interpenetrating gallol functionalized tissue adhesive hyaluronic acid hydrogel polarizes macrophages to an immunosuppressive phenotype
Ingår i Acta Biomaterialia, s. 36-48, 2022.
DOI för Interpenetrating gallol functionalized tissue adhesive hyaluronic acid hydrogel polarizes macrophages to an immunosuppressive phenotype Ladda ner fulltext (pdf) av Interpenetrating gallol functionalized tissue adhesive hyaluronic acid hydrogel polarizes macrophages to an immunosuppressive phenotype
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An unexpected role of an extra phenolic hydroxyl on the chemical reactivity and bioactivity of catechol or gallol modified hyaluronic acid hydrogels
Ingår i Polymer Chemistry, s. 2987-2991, 2021.
DOI för An unexpected role of an extra phenolic hydroxyl on the chemical reactivity and bioactivity of catechol or gallol modified hyaluronic acid hydrogels Ladda ner fulltext (pdf) av An unexpected role of an extra phenolic hydroxyl on the chemical reactivity and bioactivity of catechol or gallol modified hyaluronic acid hydrogels
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Discrepancies on the Role of Oxygen Gradient and Culture Condition on Mesenchymal Stem Cell Fate
Ingår i Advanced Healthcare Materials, 2021.
DOI för Discrepancies on the Role of Oxygen Gradient and Culture Condition on Mesenchymal Stem Cell Fate Ladda ner fulltext (pdf) av Discrepancies on the Role of Oxygen Gradient and Culture Condition on Mesenchymal Stem Cell Fate
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Effect of the Addition Frequency of 5-Azacytidine in Both Micro- and Macroscale Cultures
Ingår i Cellular and Molecular Bioengineering, s. 121-130, 2021.
DOI för Effect of the Addition Frequency of 5-Azacytidine in Both Micro- and Macroscale Cultures Ladda ner fulltext (pdf) av Effect of the Addition Frequency of 5-Azacytidine in Both Micro- and Macroscale Cultures
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Redox responsive Pluronic micelle mediated delivery of functional siRNA: a modular nano-assembly for targeted delivery
Ingår i Biomaterials Science, s. 3939-3944, 2021.
DOI för Redox responsive Pluronic micelle mediated delivery of functional siRNA: a modular nano-assembly for targeted delivery Ladda ner fulltext (pdf) av Redox responsive Pluronic micelle mediated delivery of functional siRNA: a modular nano-assembly for targeted delivery
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PDMS leaching and its implications for on-chip studies focusing on bone regeneration applications
Ingår i Organs-on-a-Chip, 2020.
DOI för PDMS leaching and its implications for on-chip studies focusing on bone regeneration applications Ladda ner fulltext (pdf) av PDMS leaching and its implications for on-chip studies focusing on bone regeneration applications
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4 '-Guanidinium-modified siRNA: a molecular tool to control RNAi activity through RISC priming and selective antisense strand loading
Ingår i Chemical Communications, s. 9112-9115, 2019.
DOI för 4 '-Guanidinium-modified siRNA: a molecular tool to control RNAi activity through RISC priming and selective antisense strand loading Ladda ner fulltext (pdf) av 4 '-Guanidinium-modified siRNA: a molecular tool to control RNAi activity through RISC priming and selective antisense strand loading
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A turn-on fluorescent GFP chromophore analog for highly selective and efficient detection of H2S in aqueous and in living cells
Ingår i Sensors and actuators. B, Chemical, 2019.
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An Unexpected Role of Hyaluronic Acid in Trafficking siRNA Across the Cellular Barrier: The First Biomimetic, Anionic, Non-Viral Transfection Method
Ingår i Angewandte Chemie International Edition, s. 2815-2819, 2019.
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First Aldol Cross-Linked Hyaluronic Acid Hydrogel: Fast and Hydrolytically Stable Hydrogel with Tissue Adhesive Properties
Ingår i ACS Applied Materials and Interfaces, s. 38232-38239, 2019.
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Impact of Hydrogel Cross-Linking Chemistry on the in Vitro and in VivoBioactivity of Recombinant Human Bone Morphogenetic Protein-2
Ingår i ACS Applied Bio Materials, 2019.
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Influence of ions to modulate hydrazone and oxime reaction kinetics to obtain dynamically cross-linked hyaluronic acid hydrogels
Ingår i Polymer Chemistry, s. 4322-4327, 2019.
DOI för Influence of ions to modulate hydrazone and oxime reaction kinetics to obtain dynamically cross-linked hyaluronic acid hydrogels Ladda ner fulltext (pdf) av Influence of ions to modulate hydrazone and oxime reaction kinetics to obtain dynamically cross-linked hyaluronic acid hydrogels
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Innovative strategy for 3D transfection of primary human stem cells with BMP-2 expressing plasmid DNA: A clinically translatable strategy for ex vivogene therapy
Ingår i International Journal of Molecular Sciences, 2019.
DOI för Innovative strategy for 3D transfection of primary human stem cells with BMP-2 expressing plasmid DNA: A clinically translatable strategy for ex vivogene therapy Ladda ner fulltext (pdf) av Innovative strategy for 3D transfection of primary human stem cells with BMP-2 expressing plasmid DNA: A clinically translatable strategy for ex vivogene therapy
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Insights into siRNA Transfection in Suspension: Efficient Gene Silencing in Human Mesenchymal Stem Cells Encapsulated in Hyaluronic Acid Hydrogel
Ingår i Biomacromolecules, s. 1317-1324, 2019.
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MicroRNA detection based on duplex-specific nuclease-assisted target recycling and gold nanoparticle/graphene oxide nanocomposite-mediated electrocatalytic amplification
Ingår i Biosensors & bioelectronics, s. 188-193, 2019.
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Modulating thiol pKa promotes disulfide formation at physiological pH: An elegant strategy to design disulfide cross-linked hyaluronic acid hydrogels
Ingår i Biomacromolecules, s. 1412-1420, 2019.
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Synthetic design of asymmetric miRNA with engineered 3′-overhang to improve strand selection
Ingår i Molecular Therapy - Nucleic Acids, s. 597-604, 2019.
DOI för Synthetic design of asymmetric miRNA with engineered 3′-overhang to improve strand selection Ladda ner fulltext (pdf) av Synthetic design of asymmetric miRNA with engineered 3′-overhang to improve strand selection
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Saline Accelerates Oxime Reaction with Aldehyde and Keto Substrates at Physiological pH
Ingår i Scientific Reports, 2018.
DOI för Saline Accelerates Oxime Reaction with Aldehyde and Keto Substrates at Physiological pH Ladda ner fulltext (pdf) av Saline Accelerates Oxime Reaction with Aldehyde and Keto Substrates at Physiological pH
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Thiazolidine chemistry revisited: a fast, efficient and stable click-type reaction at physiological pH
Ingår i Chemical Communications, s. 12507-12510, 2018.
DOI för Thiazolidine chemistry revisited: a fast, efficient and stable click-type reaction at physiological pH Ladda ner fulltext (pdf) av Thiazolidine chemistry revisited: a fast, efficient and stable click-type reaction at physiological pH
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Host cell recruitment patterns by bone morphogenetic protein-2 releasing hyaluronic acid hydrogels in a mouse subcutaneous environment
Ingår i Regenerative Medicine, s. 525-539, 2017.
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Injectable and thermoresponsive pericardial matrix derived conductive scaffold for cardiac tissue engineering
Ingår i RSC Advances, s. 31980-31988, 2017.
DOI för Injectable and thermoresponsive pericardial matrix derived conductive scaffold for cardiac tissue engineering Ladda ner fulltext (pdf) av Injectable and thermoresponsive pericardial matrix derived conductive scaffold for cardiac tissue engineering
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Chondroitin sulfate derived theranostic nanoparticles for targeted drug delivery
Ingår i Biomaterials Science, s. 1310-1313, 2016.
DOI för Chondroitin sulfate derived theranostic nanoparticles for targeted drug delivery
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Multifunctional Hyaluronic Acid and Chondroitin Sulfate Nanoparticles: Impact of Glycosaminoglycan Presentation on Receptor Mediated Cellular Uptake and Immune Activation
Ingår i ACS Applied Materials and Interfaces, s. 20614-20624, 2016.
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2 '-N-Guanidino, 4 '-C-ethylene bridged thymidine (GENA-T) modified oligonucleotide exhibits triplex formation with excellent enzymatic stability
Ingår i RSC Advances, s. 12257-12260, 2015.
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Chondroitin Sulfate-Coated DNA-Nanoplexes Enhance Transfection Efficiency by Controlling Plasmid Release from Endosomes: A New Insight into Modulating Nonviral Gene Transfection
Ingår i Advanced Functional Materials, s. 3907-3915, 2015.
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Insights into the Mechanism and Catalysis of Oxime Coupling Chemistry at Physiological pH
Ingår i Chemistry - A European Journal, s. 5980-5985, 2015.
DOI för Insights into the Mechanism and Catalysis of Oxime Coupling Chemistry at Physiological pH
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Cell type and transfection reagent-dependent effects on viability, cell content, cell cycle and inflammation of RNAi in human primary mesenchymal cells
Ingår i European Journal of Pharmaceutical Sciences, s. 35-44, 2014.
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Host cell recruitment patterns by BMP-2 releasing hyaluronic acid gels in a mouse subcutaneous model
Ingår i Journal of Tissue Engineering and Regenerative Medicine, s. 65-65, 2014.
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Mild and Efficient Strategy for Site-Selective Aldehyde Modification of Glycosaminoglycans: Tailoring Hydrogels with Tunable Release of Growth Factor
Ingår i Biomacromolecules, s. 2427-2432, 2013.
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PLGA/PEG-hydrogel composite scaffolds with controllable mechanical properties
Ingår i Journal of Biomedical Materials Research. Part B - Applied biomaterials, s. 648-655, 2013.
DOI för PLGA/PEG-hydrogel composite scaffolds with controllable mechanical properties
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Smart Design of Stable Extracellular Matrix Mimetic Hydrogel: Synthesis, Characterization, and In Vitro and In Vivo Evaluation for Tissue Engineering
Ingår i Advanced Functional Materials, s. 1273-1280, 2013.
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Critical Assessment of rhBMP-2 Mediated Bone Induction: an In Vitro and In Vivo Evaluation
Ingår i Journal of Tissue Engineering and Regenerative Medicine, s. 39-39, 2012.
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Critical assessment of rhBMP-2 mediated bone induction: An in vitro and in vivo evaluation.
Ingår i Journal of Controlled Release, s. 646-653, 2012.
DOI för Critical assessment of rhBMP-2 mediated bone induction: An in vitro and in vivo evaluation.
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Injectable hyaluronic acid hydrogel for bone tissue engineering
Ingår i European Cells and Materials, s. 2-, 2012.
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Keynote: Safe and efficient in-vivo gene gene transfer and silencing technologies using natural pathways
Ingår i Journal of Tissue Engineering and Regenerative Medicine, s. 190-190, 2012.
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Minimally invasive mandibular bone augmentation using injectable hydrogels
Ingår i Journal of Tissue Engineering and Regenerative Medicine, s. s15-s23, 2012.
DOI för Minimally invasive mandibular bone augmentation using injectable hydrogels
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Smart design of stable hydrazone crosslinked extracellular matrix mimetic hydrogel for tissue engineering application
Ingår i Journal of Tissue Engineering and Regenerative Medicine, s. 192-192, 2012.
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Bone reservoir: Injectable hyaluronic acid hydrogel for minimal invasive bone augmentation
Ingår i Journal of Controlled Release, s. 232-240, 2011.
DOI för Bone reservoir: Injectable hyaluronic acid hydrogel for minimal invasive bone augmentation
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Functionalization of Hyaluronic Acid with Chemoselective Groups via a Disulfide-Based Protection Strategy for In Situ Formation of Mechanically Stable Hydrogels
Ingår i Biomacromolecules, s. 2247-2254, 2010.
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Modular approach to functional hyaluronic acid hydrogels using orthogonal chemical reactions
Ingår i Chemical Communications, s. 8368-8370, 2010.
DOI för Modular approach to functional hyaluronic acid hydrogels using orthogonal chemical reactions
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Synthesis of Guanidinium-Modified Hyaluronic Acid Hydrogel
Ingår i Macromolecular rapid communications, s. 1175-1180, 2010.
DOI för Synthesis of Guanidinium-Modified Hyaluronic Acid Hydrogel
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In Situ Cross-Linkable High Molecular Weight Hyaluronan−Bisphosphonate Conjugate for Localized Delivery and Cell-Specific Targeting: A Hydrogel Linked Prodrug Approach
Ingår i Journal of the American Chemical Society, s. 8781-8783, 2009.
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Comparison of the RNase H Cleavage Kinetics and Blood Serum Stability of the North-Conformationally Constrained and 2‘-Alkoxy Modified Oligonucleotides
Ingår i Biochemistry, s. 5635-5646, 2007.
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Conformationally Constrained 2'-N,4'-C-Ethylene-Bridged Thymidine (Aza-ENA-T): Synthesis, Structure, Physical, and Biochemical Studies of Aza-ENA-T-Modified Oligonucleotides
Ingår i Journal of the American Chemical Society, s. 15173-15187, 2006.
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Synthesis and Structure of Novel Conformationally-constrained 1'2'-Azetidine-Fused Bicyclic Pyrimidine Nucleosides: Their Incorporation into Oligo-DNAs and the Thermal Stability of the Heteroduplexes
Ingår i Journal of Organic Chemistry, s. 299-314, 2006.
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The chemical nature of the 2'-substituent in the pentose-sugar dictates the pseudoaromatic character of the nucleobase (pKa) in DNA/RNA.
Ingår i Org. Biomol. Chem., s. 1675-1686, 2006.
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The chemical nature of the 2'-substituent in the pentosesugar dictates the pseudoaromatic character of the nucleobase (pKa) in DNA/RNA
Ingår i Org Biomol Chem, s. 1675-1686, 2006.
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First Aldol-Crosslinked Hyaluronic Acid Hydrogel: Fast and Hydrolytically Stable Gel with Tissue Adhesive Properties
Ingår i Chemical Sciences Journal