Molecules that recognize and bind proteins are indispensable in biotechnology and drug development. We develop new molecular concepts for protein recognition "outside of the box" and based on fundamental chemical principles of molecular recognition.
Christine Dyrager: Targeting hypoxia in cancer therapy and diagnosis
Organic synthesis of luminescent heterocyclic compounds, target-specific imaging agents, and hypoxia-activated prodrugs.
Lars Engman: Design, synthesis and application of novel catalytic antioxidants
Design, synthesis and testing of novel catalytic antioxidants. Biologically active organochalcogen compounds. Radical chemistry.
The Quantum Chemistry Group
Electronic structure and dynamics simulations, and modelling of electronic structure theory plays a central role in our research projects. Current applications include simulations of properties of chemiluminescent molecules, photochemistry, and interpretation of spectra. Developments are focused on multi-configurational wave function theoryand their implementations in the software package OpenMolcas.
Halogen bonding, antimalarial natural products from plants in East Africa, paramagnetic ligand tagging technology and development of Metallo-Beta-Lactamase inhibitors to control antibiotic resistance.
Adolf Gogoll: Functional molecular entities
Organic synthesis of functional entities: Supramolecular host-guest systems, photoswitchable peptidomimetics, and monomers for conducting redox polymers. Our main tools are organometallic synthesis, peptide synthesis, and NMR spectroscopy.
Helena Grennberg: Graphene from a molecular perspective
Purification, derivatisation and evaluations of fullerenes and carbon nanotubes; synthesis and chemical functionalization of graphene. Dyes and dyads for electron transfer studies, solar cells and molecular electronics applications. Supramolecular and organometallic chemistry. (No web page yet.)
Jan Kihlberg: Chemical tools for research and drug discovery beyond traditional drug space
Chemical probes for difficult targets that conquer complex disease.
Lukasz Pilarski: Synthetic methodology, catalysis and green chemistry
The group pursues the development of faster, cheaper and greener organic transformations using C-H activation, arynes and mechanochemistry.