Section of Chemistry

Publications

  • Sundell, Gustav; Vögeli, Beat; Ivarsson, Ylva; Chi, Celestine N. et al.

    The Sign of Nuclear Magnetic Resonance Chemical Shift Difference as a Determinant of the Origin of Binding Selectivity: Elucidation of the Position Dependence of Phosphorylation in Ligands Binding to Scribble PDZ1

    Part of Biochemistry, p. 66-71, 2018.

  • Wigington, C. P.; Roy, J.; Damle, N. P.; Ulengin-Talkish, I. et al.

    A novel role for the Calcineurin phosphatase at the nuclear pore

    Part of Molecular Biology of the Cell, p. 3727-3727, 2017.

  • Davey, Norman E.; Seo, Moon-Hyeong; Yadav, Vikash Kumar; Jeon, Jouhyun et al.

    Discovery of short linear motif-mediated interactions through phage display of intrinsically disordered regions of the human proteome

    Part of The FEBS Journal, p. 485-498, 2017.

  • Cho, S. Ei; Roy, J.; Ivarsson, Ylva; Cyert, M. S. et al.

    Investigating the phospho-regulation of ER shaping protein RTN1A (Reticulon-1A) by the Calcineurin phosphatase.

    Part of Molecular Biology of the Cell, p. 3727-3727, 2017.

  • Roy, J.; Wigington, C. P.; Damle, N. P.; Ulengin-Talkish, I. et al.

    Mapping the human calcineurin phosphatase signaling network through global identification of short linear motifs that mediate substrate recognition

    Part of Molecular Biology of the Cell, p. 3727-3727, 2017.

  • Wu, Cheng-Guo; Chen, Hui; Guo, Feng; Yadav, Vikash K et al.

    PP2A-B' holoenzyme substrate recognition, regulation and role in cytokinesis

    Part of Cell Discovery, 2017.

  • Wigington, Callie P.; Roy, Jagoree; Damle, Nikhil P.; El Cho, Shein et al.

    Uncovering Novel Substrates and Functions for the Calcineurin Phosphatase in Human Cells

    Part of The FASEB Journal, 2017.

  • Egea-Jimenez, Antonio Luis; Gallardo, Rodrigo; Garcia-Pino, Abel; Ivarsson, Ylva et al.

    Frizzled 7 and PIP2 binding by syntenin PDZ2 domain supports Frizzled 7 trafficking and signalling

    Part of Nature Communications, 2016.

  • Karlsson, O Andreas; Sundell, Gustav N; Andersson, Eva; Ivarsson, Ylva et al.

    Improved affinity at the cost of decreased specificity: a recurring theme in PDZ-peptide interactions.

    Part of Scientific Reports, 2016.

  • Raykova, Doroteya; Koos, Bjoern; Asplund, Anna; Gelleri, Marton et al.

    Let There Be Light!

    Part of Proteomes, 2016.

  • Nim, Satra; Jeon, Jouhyun; Corbi-Verge, Carles; Seo, Moon-Hyeong et al.

    Pooled screening for antiproliferative inhibitors of protein-protein interactions.

    Part of Nature Chemical Biology, p. 275-281, 2016.

  • Garrido-Urbani, Sarah; Garg, Pankaj; Ghossoub, Rania; Arnold, Roland et al.

    Proteomic peptide phage display uncovers novel interactions of the PDZ1-2 supramodule of syntenin

    Part of FEBS Letters, p. 3-12, 2016.

  • Wigington, C. P.; Damle, N. P.; Roy, J.; Cho, S. E. et al.

    Uncovering novel substrates and functions for the calcineurin phosphatase in human cells.

    Part of Molecular Biology of the Cell, 2016.

  • Blikstad, Cecilia; Ivarsson, Ylva

    High-throughput methods for identification of protein-protein interactions involving short linear motifs

    Part of Cell Communication and Signaling, 2015.

  • Ganesan, Ashok; Debulpaep, Maja; Wilkinson, Hannah; Van Durme, Joost et al.

    Selectivity of Aggregation-Determining Interactions

    Part of Journal of Molecular Biology, p. 236-247, 2015.

  • Ilari, Andrea; Fiorillo, Annarita; Poser, Elena; Lalioti, Vasiliki S. et al.

    Structural basis of Sorcin-mediated calcium-dependent signal transduction

    Part of Scientific Reports, 2015.

  • Ernst, Andreas; Appleton, Brent A; Ivarsson, Ylva; Zhang, Yingnan et al.

    A Structural Portrait of the PDZ Domain Family

    Part of Journal of Molecular Biology, p. 3509-3519, 2014.

  • Sundell, Gustav; Ivarsson, Ylva

    Interaction Analysis through Proteomic Phage Display

    Part of BioMed Research International, p. 176172-, 2014.

  • Ivarsson, Ylva; Arnold, Roland; McLaughlin, Megan; Nim, Satra et al.

    Large-scale interaction profiling of PDZ domains through proteomic peptide-phage display using human and viral phage peptidomes

    Part of Proceedings of the National Academy of Sciences of the United States of America, p. 2542-2547, 2014.

  • Haugaard-Kedstrom, L. M.; Albertsen, L.; Gil, F. Abalde; Ivarsson, Ylva et al.

    The Development and Characterization of a Peptide-Based Syntenin Inhibitor: Implacations for Cancer Metastasis

    Part of Journal of Peptide Science, p. S39-S39, 2014.

  • Hämälistö, Saara; Pouwels, Jeroen; de Franceschi, Nicola; Saari, Markku et al.

    A ZO-1/α5β1-integrin complex regulates cytokinesis downstream of PKCε in NCI-H460 cells plated on fibronectin

    Part of PLoS ONE, p. e70696-, 2013.

  • Ivarsson, Ylva; Wawrzyniak, Anna Maria; Kashyap, Rudra; Polanowska, Jolanta et al.

    Prevalence, specificity and determinants of lipid-interacting PDZ domains from an in-cell screen and in vitro binding experiments

    Part of PloS one, p. e54581-, 2013.

  • Wawrzyniak, Anna Maria; Vermeiren, Elke; Zimmermann, Pascale; Ivarsson, Ylva et al.

    Extensions of PSD-95/discs large/ZO-1 (PDZ) domains influence lipid binding and membrane targeting of syntenin-1

    Part of FEBS Letters, p. 1445-1451, 2012.

  • Ivarsson, Ylva

    Plasticity of PDZ domains in ligand recognition and signaling

    Part of FEBS Letters, p. 2638-47, 2012.

  • Baietti, Maria Francesca; Zhang, Zhe; Mortier, Eva; Melchior, Aurélie et al.

    Syndecan-syntenin-ALIX regulates the biogenesis of exosomes

    Part of Nature cell biology, p. 677-685, 2012.

  • Lambaerts, Kathleen; Van Dyck, Stijn; Mortier, Eva; Ivarsson, Ylva et al.

    Syntenin, a syndecan adaptor and an Arf6 phosphatidylinositol 4,5-bisphosphate effector, is essential for epiboly and gastrulation cell movements in zebrafish

    Part of Journal of Cell Science, p. 1129-1140, 2012.

  • Ivarsson, Ylva; Wawrzyniak, Anna Maria; Wuytens, Gunther; Kosloff, Mickey et al.

    Cooperative phosphoinositide and peptide binding by PSD-95/discs large/ZO-1 (PDZ) domain of polychaetoid, Drosophila zonulin

    Part of Journal of Biological Chemistry, p. 44669-78, 2011.

  • Fugier, Charlotte; Klein, Arnaud F; Hammer, Caroline; Vassilopoulos, Stéphane et al.

    Misregulated alternative splicing of BIN1 is associated with T tubule alterations and muscle weakness in myotonic dystrophy

    Part of Nature medicine, p. 720-725, 2011.

  • Gianni, Stefano; Ivarsson, Ylva; De Simone, Alfonso; Travaglini-Allocatelli, Carlo et al.

    Structural characterization of a misfolded intermediate populated during the folding process of a PDZ domain

    Part of Nature Structural & Molecular Biology, p. 1431-1437, 2010.

  • Gallardo, Rodrigo; Ivarsson, Ylva; Schymkowitz, Joost; Rousseau, Frédéric et al.

    Structural diversity of PDZ-lipid interactions

    Part of ChemBioChem (Print), p. 456-67, 2010.

  • Ivarsson, Ylva; Travaglini-Allocatelli, Carlo; Brunori, Maurizio; Gianni, Stefano et al.

    Engineered symmetric connectivity of secondary structure elements highlights malleability of protein folding pathways

    Part of Journal of the American Chemical Society, p. 11727-33, 2009.

  • Travaglini-Allocatelli, Carlo; Ivarsson, Ylva; Jemth, Per; Gianni, Stefano et al.

    Folding and stability of globular proteins and implications for function

    Part of Current opinion in structural biology, p. 3-7, 2009.

  • Ivarsson, Ylva; Travaglini-Allocatelli, Carlo; Brunori, Maurizio; Gianni, Stefano et al.

    Folding and misfolding in a naturally occurring circularly permuted PDZ domain

    Part of Journal of Biological Chemistry, p. 8954-60, 2008.

  • Ivarsson, Ylva; Travaglini-Allocatelli, Carlo; Brunori, Maurizio; Gianni, Stefano et al.

    Mechanisms of protein folding

    Part of European Biophysics Journal, p. 721-728, 2008.

  • Ivarsson, Ylva; Travaglini-Allocatelli, Carlo; Morea, Veronica; Brunori, Maurizio et al.

    The folding pathway of an engineered circularly permuted PDZ domain

    Part of Protein Engineering Design & Selection, p. 155-160, 2008.

  • Ivarsson, Ylva; Travaglini-Allocatelli, Carlo; Jemth, Per; Malatesta, Francesco et al.

    An on-pathway intermediate in the folding of a PDZ domain

    Part of Journal of Biological Chemistry, p. 8568-8572, 2007.

  • Ivarsson, Ylva; Norrgård, Malena A.; Hellman, Ulf; Mannervik, Bengt et al.

    Engineering the enantioselectivity of glutathione transferase by combined active-site mutations and chemical modifications

    Part of Biochimica et Biophysica Acta - General Subjects, p. 1374-1381, 2007.

  • Gianni, Stefano; Ivarsson, Ylva; Jemth, Per; Brunori, Maurizio et al.

    Identification and characterization of protein folding intermediates

    Part of Biophysical Chemistry, p. 105-113, 2007.

  • Gianni, Stefano; Ivarsson, Ylva; Bah, Alaji; Bush-Pelc, Leslie A et al.

    Mechanism of Na(+) binding to thrombin resolved by ultra-rapid kinetics

    Part of Biophysical Chemistry, p. 111-114, 2007.

  • Norrgård, Malena A.; Ivarsson, Ylva; Tars, Kaspars; Mannervik, Bengt et al.

    Alternative mutations of a positively selected residue elicit gain or loss of functionalities in enzyme evolution

    Part of Proceedings of the National Academy of Sciences of the USA, p. 4876 4876-4881 4881, 2006.

  • Norrgård, Malena A; Ivarsson, Ylva; Tars, Kaspars; Mannervik, Bengt et al.

    Alternative mutations of a positively selected residue elicit gain or loss of functionalities in enzyme evolution

    Part of Proceedings of the National Academy of Sciences of the United States of America, p. 4876-4881, 2006.

  • Ivarsson, Ylva; Mannervik, Bengt

    Combinatorial protein chemistry in three dimensions: a paradigm for the evolution of glutathione transferases with novel activities

    Part of Toxicology of Glutathione Transferases, p. 47-69, 2006.

  • Ivarsson, Ylva; Mannervik, Bengt

    Regio- and enantioselectivity in epoxide conjugations are modulated by residue 210 in Mu class glutathione transferases

    Part of Protein Engineering Design and Selection, p. 607 607-616 616, 2006.

  • Ivarsson, Ylva; Mannervik, Bengt

    Exploring the importance of an active site residue on the stereo and regio selectivity of Mu class glutathione transferases

    Part of FEBS Journal, p. 88 Suppl-, 2005.

  • Ivarsson, Ylva; Mannervik, Bengt

    Regio- and enantioselectivities in epoxide conjugations are modulated by residue 210 in Mu class glutathione transferases.

    Part of Protein Eng Des Sel, p. 607-16, 2005.

  • Ivarsson, Ylva; Mackey, Aaron J.; Edalat, Maryam; Pearson, William R. et al.

    Identification of residues in glutathione transferase capable of driving functional diversification in evolution: A novel approach to protein redesign

    Part of Journal of Biological Chemistry, p. 8733 8733-8738 8738, 2003.

  • Ivarsson, Ylva; Jemth, Per

    Affinity and specificity of motif-based protein-protein interactions

    Part of Current opinion in structural biology